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Amines REACH

n-formylmorpholine

CAS Number
4394-85-8
EC Number
224-518-3
Chemical Formula
C5H9NO2
Molecular Weight
115.13 g/mol

Description

N-Formylmorpholine (CAS 4394-85-8 ), commonly abbreviated as NFM, is a polar aprotic solvent used across pharmaceutical synthesis, polymer processing, and industrial cleaning applications. Its high solvating power and thermal stability make it a preferred alternative to more regulated solvents in demanding process environments. In pharmaceutical manufacturing, NFM functions as a reaction solvent. It is used as a carrier in active ingredient synthesis, particularly where low volatility and chemical inertness are process requirements. Polymer processors use it to dissolve and spin aromatic polyamides. This includes applications in fiber and membrane production lines for engineering polymers. Industrial and institutional cleaning formulators incorporate NFM into heavy-duty degreasers targeting resins and coatings. It is effective against adhesive residues on industrial equipment and serves as a catalyst solvent. In specialty chemical synthesis, its controlled polarity is critical to achieving high reaction yields. NFM is supplied as a liquid in bulk quantities, with intermediate packaging available in drums and IBCs. Technical grade is the standard commercial offering for most industrial applications. High-purity grades are available to meet pharmaceutical and specialty chemical process specifications. Buyers should confirm purity thresholds and water content limits against internal process requirements when sourcing. Contact us for supply of n-formylmorpholine Request Quote

Other Names (Synonyms)

morpholine-4-carbaldehyde | 4-morpholinecarbaldehyde | 4-Formylmorpholine | 4-Morpholinecarboxaldehyde | Morpholine, 4-formyl- | D1E63XO4RH | NFM

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point21 °C
Boiling Point234-238 °C
Density1.145 g/cm³ (liquid)
Flash Point>230 °F
AppearanceCLEAR YELLOW LIQUID
ColorClear yellow
FormLiquid
Water SolubilitySOLUBLE
Vapor Pressure0.03 hPa (20 °C)
Refractive Indexn 20/D 1.485(lit.)
pH10 (250g/l, H2O, 20℃)
Log P-1.2 at 23℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H317
H317
H319
H319
H335H335

Precautionary Statements

P261
P261
P271
P271
P272
P272
P280
P280
P319
P319
P321
P321
P405
P405
P501
P501
P265
P265
P352
P352
P340
P340
P317
P317
P317
P317
P364
P364
P233
P233
P338

Trade & Regulatory

HS Code29349990
Storage Class11 - Combustible Solids
WGK (Germany)3