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Dimethylformamide

CAS Number
68-12-2
EC Number
200-679-5
Chemical Formula
C3H7NO
Molecular Weight
73.09 g/mol

Description

Dimethylformamide ( CAS 68-12-2 ), commercially known as DMF, is a high-boiling polar aprotic solvent used across chemical manufacturing, pharmaceutical synthesis, and industrial processing. Its ability to dissolve a broad range of organic and inorganic compounds makes it a preferred solvent where water-miscible, low-volatility performance is required for complex reactions. In pharmaceutical manufacturing, DMF serves as a reaction solvent and purification medium for active pharmaceutical ingredients, where controlled solvation and high purity grades are critical. Acrylic fiber and synthetic leather production rely on DMF to dissolve and process polyacrylonitrile and polyurethane resins into spinnable or coatable forms for industrial use. Electronics manufacturers use it to strip and clean photoresist layers during PCB and semiconductor fabrication. In agrochemical synthesis, DMF functions as both a solvent and a catalyst precursor. DMF is supplied as a clear liquid in drums, IBCs, and bulk tanker quantities. Standard commercial grades include technical grade and high-purity pharmaceutical grade for various needs. Specifications are aligned to USP and Ph. Eur. pharmacopeial standards where API manufacturing requires it. Low-water and anhydrous variants are available for moisture-sensitive synthesis. Contact us for supply of Dimethylformamide Request Quote

Other Names (Synonyms)

N,N-Dimethylformamide | N-Formyldimethylamine | Dimethylamid kyseliny mravenci | DMF | Formamide, N,N-dimethyl- | DMFA | Dimethylformamide DMF

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-61 °C
Boiling Point153 °C @ Press: 760 Torr
Density0.9445 g/cm³ @ Temp: 25 °C
Flash Point136 °F
AppearanceClear colorless liquid
ColorAPHA: ≤15
OdorFaint, ammonia-like odor detectable at 100 ppm
FormPowder
Water Solubilitysoluble
Vapor Pressure2.7 mm Hg ( 20 °C)
Refractive Indexn 20/D 1.430(lit.)
pH7 (200g/l, H2O, 20℃)
Log P-1.010

Safety & Handling

Danger
GHS07· IrritantGHS08· Health HazardGHS02· FlammableGHS06· ToxicGHS05· Corrosive

Hazard Statements

H226Flammable liquid and vapor
H303May be harmful if swallowed
H312Harmful in contact with skin
H313May be harmful in contact with skin
H315Causes skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H320Causes eye irritation
H331Toxic if inhaled
H332Harmful if inhaled
H341Suspected of causing genetic defects
H350May cause cancer
H360May damage fertility or the unborn child
H370Causes damage to organs
H371May cause damage to organs
H372Causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29241990
UN Number2265
ADR Class3
Packing GroupIII
Storage Class3 - Flammable liquids
WGK (Germany)1