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Solvents REACH

Diethylformamide

CAS Number
617-84-5
EC Number
210-533-2
Chemical Formula
C5H11NO
Molecular Weight
101.15 g/mol

Description

Diethylformamide ( CAS 617-84-5 ), commonly abbreviated as DEF, is a high-boiling polar aprotic solvent used across pharmaceutical synthesis, polymer processing, and specialty chemical manufacturing. It functions as a reaction medium and carrier solvent where controlled solvation and thermal stability are required. In pharmaceutical manufacturing, DEF serves as a process solvent for active ingredient synthesis. It is utilized in purification steps where a high-boiling amide solvent is needed with lower toxicity concerns than DMF. Polymer and resin processors use it to dissolve or disperse specialty polymers. This solvent is ideal for compounding and coating operations. In printing and packaging, DEF is incorporated into ink formulations and surface treatment processes that require a stable, slow-evaporating solvent. This helps to control drying profiles effectively. It also functions as a reaction solvent in fine chemical synthesis where precise control over polarity and boiling point influences reaction selectivity. DEF is supplied as a clear liquid in drums and IBC containers, with bulk quantities available for industrial procurement. Technical grade is the standard commercial offering for most industrial uses. Purity specifications are typically at 99% or higher. Buyers sourcing for pharmaceutical applications should confirm GMP compliance and batch documentation with the supplier to ensure quality standards. Contact us for supply of Diethylformamide Request Quote

Other Names (Synonyms)

N,N-diethylformamide | Formamide, N,N-diethyl- | N-Formyldiethylamine | Diethylamid kyseliny mravenci | D4BLP8BN9H | DEF

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-60.5 °C
Boiling Point177 °C
Density0.908 g/cm³
Flash Point141 °F
Appearanceclear colorless to pale yellow liquid
ColorClear colorless to pale yellow
FormLiquid
Refractive Indexn 20/D 1.434(lit.)

Safety & Handling

Warning
GHS02· FlammableGHS07· Irritant

Hazard Statements

H226Flammable liquid and vapor
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29241990
UN Number1993
ADR Class3
Packing GroupIII
WGK (Germany)1