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n-ethylmorpholine

CAS Number
100-74-3
EC Number
202-885-0
Chemical Formula
C6H13NO
Molecular Weight
115.17 g/mol

Description

N-Ethylmorpholine (CAS 100-74-3 ), commonly abbreviated as NEM, is a tertiary amine used as a catalyst and pH-regulating agent across specialty chemical manufacturing. It functions as a reactive intermediate and process catalyst. This chemical serves as a solvent in systems where controlled basicity and miscibility with polar media are required. In polyurethane production, NEM acts as a blowing and gelation catalyst, influencing foam cell structure. It is used in both flexible and rigid foam formulations to manage the cure rate effectively. Coatings and resin manufacturers use it as a neutralizing amine to stabilize waterborne systems and adjust pH levels. The compound is particularly useful in acrylic and alkyd dispersions. Pharmaceutical synthesis relies on NEM as a non-nucleophilic base and reaction solvent in multi-step organic processes where selectivity is critical. Mild basicity makes it an ideal choice for sensitive chemical reactions. In metalworking fluids and lubricant concentrates, it functions as a corrosion inhibitor component and an effective emulsion stabilizer. N-Ethylmorpholine is supplied as a clear liquid, typically in drum and IBC quantities for industrial buyers. Technical grade is the standard commercial offering for most large-scale manufacturing applications. High-purity grades are available for pharmaceutical and fine chemical applications. Specifications vary by supplier, with purity levels commonly at 99% or above for process-critical uses in various industries. Contact us for supply of n-ethylmorpholine Request Quote

Other Names (Synonyms)

4-ethylmorpholine | Morpholine, 4-ethyl- | N-Ethylmorfolin | ECM0G991FQ | NEM

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-62.78 °C
Boiling Point138-139 °C @ Press: 763 Torr
Density0.8996 g/cm³ @ Temp: 20 °C
Flash Point82 °F
Appearance4-Ethylmorpholine is a colorless liquid with an ammonia-like odor.
ColorCream to beige to brown-grey
FormPowder
Water Solubilitymiscible
Vapor Pressure8.1 hPa (20 °C)
Refractive Indexn 20/D 1.441(lit.)
pH11.8 (100g/l, H2O, 20℃)
Log P0.08 at 24.6℃

Safety & Handling

Danger
GHS02· FlammableGHS05· CorrosiveGHS06· ToxicGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H226Flammable liquid and vapor
H302Harmful if swallowed
H311Toxic in contact with skin
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H316Causes mild skin irritation
H318Causes serious eye damage
H319Causes serious eye irritation
H320Causes eye irritation
H331Toxic if inhaled
H332Harmful if inhaled
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child
H371May cause damage to organs
H373May causes damage to organs through prolonged or repeated exposure H302+H312+
H332Harmful if swallowed, in contact with skin or if inhaled

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off immediately all contaminated clothing and wash it before reuse.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29349990
UN Number2920
ADR Class8
Packing GroupII
Storage Class3 - Flammable liquids
WGK (Germany)1