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Lamotrigine

CAS Number
84057-84-1
EC Number
281-901-8
Chemical Formula
C9H7Cl2N5
Molecular Weight
256.09 g/mol

Description

Lamotrigine (CAS 84057-84-1 ), marketed under the brand name Lamictal®, is an established active pharmaceutical ingredient used in the treatment of epilepsy and bipolar disorder. As a finished API and pharmaceutical intermediate, it serves as the basis for a broad range of prescription solid dosage formulations manufactured globally by pharmaceutical companies. This compound is primarily sourced by generic drug manufacturers producing tablets, chewable dispersible tablets, and extended-release oral solid forms for various neurological indications. Contract development and manufacturing organizations procure it as a key API input for formulation development projects targeting regulated markets including the US, EU, and emerging economies. Pharmaceutical importers and distributors handling controlled substance supply chains source it to fulfill hospital, pharmacy, and tender requirements for healthcare systems worldwide. It also functions as a reference standard or synthetic building block for research institutions and API developers working on triazine-based heterocyclic compounds and related chemistry. The product is supplied as a white to off-white crystalline powder. It is available in USP , BP , and Ph. Eur. pharmacopoeial grades to meet specification requirements. Bulk quantities are typically offered in kilogram and multi-kilogram packaging with full regulatory documentation including CoA, DMF references, and ICH-compliant impurity profiles. Contact us for supply of Lamotrigine Request Quote

Other Names (Synonyms)

Lamictal® | Gizord | 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine | Qín | Qin | 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine | Lamictal Cd | Lamictal XR

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point216-218 °C
Boiling Point503.1±60.0 °C(Predicted)
Density1.572±0.06 g/cm3(Predicted)
Flash Point9°C
AppearanceWhite to Cream Coloured Powder
Colorwhite
Formpowder

Safety & Handling

Danger
GHS06· ToxicGHS08· Health Hazard

Hazard Statements

H301Toxic if swallowed
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H410Very toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy and while nursing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29336990
UN Number2811
ADR Class6.1
Packing GroupIII
WGK (Germany)3