HomeProducts

Olanzapine

CAS Number
132539-06-1
EC Number
603-618-4
Chemical Formula
C17H20N4S
Molecular Weight
312.4 g/mol

Description

Olanzapine (CAS 132539-06-1 ), also referenced in procurement as LY-170053, is an atypical antipsychotic active pharmaceutical ingredient used in the manufacture of finished-dose psychiatric medications. It is the primary API in treatments targeting schizophrenia and bipolar disorder, supplied to pharmaceutical manufacturers for tablet, orally disintegrating tablet, and injectable formulations. The largest commercial demand comes from solid oral dosage manufacturers producing conventional film-coated tablets for long-term psychiatric maintenance therapy. These formats require high-purity API. Orally disintegrating tablet formats require tightly controlled particle size to ensure dissolution performance and dose uniformity. Injectable depot formulations represent a growing segment in the market. These specialized grades require defined polymorphic form and impurity profiles. Contract manufacturers and generic pharmaceutical producers also source the material as an intermediate for bioequivalent products. Olanzapine is supplied as a white to off-white crystalline powder. Standard commercial grades include USP , BP , and Ph. Eur. specifications for regulated market supply. ICH-compliant impurity profiling is expected for all batches. Material is typically available in kilogram and multi-kilogram quantities with GMP-certified documentation packages required for procurement. Contact us for supply of Olanzapine Request Quote

Other Names (Synonyms)

Zyprexa Zydis | Olanzapin | 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine | Olansek | Zalasta | Zyprexa Velotab | Zyprexa Intramuscular

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point195 °C
Boiling Point476.0±55.0 °C(Predicted)
Density0.260 g/cm³ (solid)
Flash Point2°C
AppearanceYellow Crystalline Powder
Coloryellow
Formpowder

Safety & Handling

Danger
GHS06· ToxicGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H301Toxic if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H336May cause drowsiness or dizziness
H373May causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29349900
UN Number2811
ADR Class6.1
Packing GroupIII
Storage Class6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany)3