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Amines REACH

Memantine

CAS Number
19982-08-2
EC Number
690-724-9
Chemical Formula
C12H21N
Molecular Weight
179.30 g/mol

Description

Memantine (CAS 19982-08-2 ), also known as 3,5-dimethyl-1-adamantanamine, is an active pharmaceutical ingredient used in the treatment of moderate-to-severe Alzheimer's disease. It functions as an NMDA receptor antagonist and is the basis for several branded and generic prescription drug products worldwide. As a finished API, it is the primary active ingredient in oral tablet and solution formulations. Generic drug manufacturers source it as a starting material or advanced intermediate for synthesis of memantine hydrochloride salt, the predominant commercial form used in dosage manufacturing. Contract development and manufacturing organizations (CDMOs) also procure it as a reference standard or process intermediate when developing extended-release formulations for global markets. Pharmaceutical companies operating in regulated markets source it for inclusion in combination therapies alongside cholinesterase inhibitors. It is supplied as a white crystalline powder for industrial use. Standard grades include USP , EP ( Ph. Eur. ), and high-purity API-grade material meeting ICH Q7 GMP requirements. These standards ensure the highest level of safety and efficacy for pharmaceutical production. Bulk quantities are available for commercial manufacturing, with smaller research and reference standard quantities also offered for analytical and development use in laboratory settings. Contact us for supply of Memantine Request Quote

Other Names (Synonyms)

3,5-dimethyltricyclo[3.3.1.1(3,7)]decan-1-amine | 3,5-dimethyl-1-aminoadamantane | 3,5-dimethyl-1-adamantanamine | 1,3-dimethylaminoadamantane | 1,3-dimethyl-5-adamantanamine | 1-amino-3,5-dimethyladamantane | 3,5-dimethyladamantan-1-amine | Memantina

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point258 °C
Boiling Point239.8±8.0 °C(Predicted)
Density1.046
ColorColorless Oil to Off-White Waxy
FormSolid
Refractive IndexnD25 1.4941

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H302Harmful if swallowed

Precautionary Statements

P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P330Rinse mouth.
P501Dispose of contents/container in accordance with local regulations.
P317Get emergency medical help.