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Abacavir sulfate

CAS Number
188062-50-2
EC Number
620-488-4
Chemical Formula
C14H18N6O.1/2H2O4S
Molecular Weight
670.7 g/mol

Description

Abacavir sulfate (CAS 188062-50-2 ), also referenced in procurement as abacavir hemisulfate or 1592U89 sulfate, is the salt form of abacavir used as the active pharmaceutical ingredient in antiretroviral drug manufacturing. It functions as a nucleoside reverse transcriptase inhibitor (NRTI) incorporated into finished dosage forms targeting HIV treatment. The primary commercial application is in the manufacture of oral solid and liquid antiretroviral formulations. These formulations include tablets, film-coated tablets, and oral solutions for HIV-1 treatment. It is used as a key API in fixed-dose combination products, where it is co-formulated alongside other antiretroviral agents. Common co-formulations include agents such as lamivudine and dolutegravir. Generic pharmaceutical manufacturers source this material for finished dosage form production under regulatory filings including ANDAs and MAAs. Specialty API distributors also supply it to formulators developing pediatric antiretroviral preparations. These oral liquid formats require high-purity, well-characterized material to ensure safety and efficacy. The product is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications conforming to USP and BP monographs for global compliance. GMP -certified material is required for regulated drug product manufacturing to meet international standards. Packaging is typically offered in controlled quantities suited to standard API handling protocols. Contact us for supply of Abacavir sulfate Request Quote

Other Names (Synonyms)

Abacavir sulphate | 1592U89 sulfate | Abacavir Hemisulfate | Abamune | Abacavir (as sulfate) | Abacaviri sulfas | J220T4J9Q2

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point222-225°C
AppearanceWhite Solid
Colorwhite to tan
Formpowder
Water Solubility1.68ug/L(32 ºC)

Safety & Handling

Danger
GHS05· CorrosiveGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H317May cause an allergic skin reaction
H318Causes serious eye damage
H341Suspected of causing genetic defects
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2933595960
Storage Class11 - Combustible Solids
WGK (Germany)3