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Rabeprazole sodium

CAS Number
117976-90-6
EC Number
629-730-3
Chemical Formula
C18H21N3O3S.Na
Molecular Weight
381.4 g/mol

Description

Rabeprazole sodium (CAS 117976-90-6 ), also marketed under the brand name Aciphex, is a proton pump inhibitor used as an active pharmaceutical ingredient in the treatment of acid-related gastrointestinal disorders. It functions by suppressing gastric acid secretion, making it a key API in finished dosage form manufacturing. Rabeprazole sodium is formulated into enteric-coated tablets and delayed-release capsules. It is used for the management of conditions such as GERD, peptic ulcers, and Zollinger-Ellison syndrome. Contract manufacturers and generic drug producers source it as a primary API for solid oral dosage forms. The material targets the gastrointestinal therapeutic segment and is also used in combination therapy formulations. It is particularly effective alongside antibiotics for H. pylori eradication regimens. Pharmaceutical formulators evaluating bioequivalence studies or generic product development will source this material to established reference standards. It is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications, with material typically conforming to USP , BP , or in-house pharmacopoeial standards depending on the supplier requirements. Packaging is offered in controlled quantities suitable for R&D through to commercial-scale API manufacturing. This ensures stability and compliance for global pharmaceutical supply chains and production. Contact us for supply of Rabeprazole sodium Request Quote

Other Names (Synonyms)

Sodium rabeprazole | Aciphex | Rabeprazole sodium salt | Rabeprazole na | LY307640 sodium | Idiazole | Aciphex Sprinkle | E-3810 SODIUM

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point140-141 °C (decomp)
AppearanceWhite Crystalline Solid
Colorwhite to beige
Formpowder
Water SolubilityH2O: 10mg/mL (clear solution)

Safety & Handling

Warning
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H371May cause damage to organs
H413May cause long lasting harmful effects to aquatic life

Precautionary Statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2933399090
WGK (Germany)3