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Clopidogrel bisulfate

CAS Number
120202-66-6
EC Number
601-679-1
Chemical Formula
C16H16ClNO2S.H2O4S
Molecular Weight
419.9 g/mol

Description

Clopidogrel bisulfate (CAS 120202-66-6 ), also marketed under the salt forms clopidogrel hydrogen sulfate, is the active pharmaceutical ingredient form of clopidogrel used in the manufacture of antiplatelet medications. It is the commercially dominant salt form selected for finished dose production due to its stability profile and processability in solid oral dosage manufacturing. Generic pharmaceutical manufacturers use it as the API in tablet formulations. These formulations target cardiovascular indications, where precise polymorph control and purity are critical to regulatory submission. Contract development and manufacturing organizations source it as a starting point for 75 mg oral solid dose products. This dosage represents the most common commercial strength globally. Formulators working on combination cardiovascular products also specify this salt form when developing fixed-dose combinations requiring compatibility with standard tablet excipients. Clopidogrel bisulfate is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications aligned with USP and EP monograph requirements for global compliance. Polymorph Form I is the standard commercially supplied crystalline form for this material. Packaging typically ranges from small analytical quantities through multi-kilogram lots to support clinical batch manufacturing. These supply options are designed to facilitate both research and commercial-scale production. The material maintains high stability and purity standards necessary for the rigorous demands of the pharmaceutical industry. Contact us for supply of Clopidogrel bisulfate Request Quote

Other Names (Synonyms)

clopidogrel hydrogen sulphate | clopidogrel hydrogen sulfate | (S)-clopidogrel bisulfate | CLOPIDOGREL SULFATE | Clopidogrel bisulphate | Clopidogrel hemisulfate | Clopidogrel BMS | Isocover

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point184 °C
Colorwhite
Formsolid

Safety & Handling

Danger
GHS05· CorrosiveGHS07· IrritantGHS09· Environment

Hazard Statements

H290May be corrosive to metals
H302Harmful if swallowed
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H332Harmful if inhaled
H335May cause respiratory irritation
H362May cause harm to breast-fed children
H411Toxic to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P234Keep only in original packaging.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy and while nursing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P390Absorb spillage to prevent material damage.
P391Collect spillage.
P405Store locked up.
P406Store in a corrosion-resistant/… container with a resistant inner liner.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29349990
WGK (Germany)3