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Acetylsalicylic acid

CAS Number
50-78-2
EC Number
200-064-1
Chemical Formula
C9H8O4
Molecular Weight
180.16 g/mol

Description

Acetylsalicylic acid (CAS 50-78-2 ) is a synthetic salicylate derivative used across pharmaceutical manufacturing, personal care formulation, and specialty chemical applications. It functions primarily as an active pharmaceutical ingredient and chemical intermediate. In pharmaceutical manufacturing, ASA is the active ingredient in analgesic, antipyretic, and antiplatelet solid dosage forms. These include tablets, effervescent formulations, and coated pellets for various medical applications. Personal care formulators incorporate it as a keratolytic and preservation-supporting agent in exfoliating creams and scalp treatments. It is also frequently utilized in the production of anti-dandruff products and skin care solutions. As a chemical intermediate, it serves in the synthesis of salicylate-based compounds where controlled acetylation is required. This versatility makes it a staple in industrial chemical synthesis and laboratory research. In food-contact and specialty applications, its antioxidant and mild acidulant properties support stabilization in defined regulatory frameworks. It plays secondary roles in preservation and pH-related formulation work across industries. Acetylsalicylic acid is supplied as a white crystalline powder in pharmaceutical and technical grades. USP , BP , and Ph.Eur. specifications are standard for pharmaceutical procurement and quality assurance. Particle size distribution is often specified for tableting or coating processes to ensure manufacturing efficiency. Bulk quantities are available for industrial buyers requiring consistent material for large-scale production runs. Pharma-grade material typically requires full documentation including CoA and residual solvent profiles. This ensures compliance with global safety standards and rigorous quality control protocols for sensitive applications. Contact us for supply of Acetylsalicylic acid Request Quote

Other Names (Synonyms)

2-acetyloxybenzoic acid | Aspirin | ASA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point135 °C
Boiling Point140 °C
Density1.40 g/cm³
Flash Point250 °C
AppearanceAcetylsalicylic acid is a white crystalline solid with a slightly bitter taste. It is odorless but hydrolyzes in moist air to give an acetic acid odor
Colorwhite
Formcrystalline
Water Solubility3.3 g/L (20 ºC)
Refractive Index1.4500 (estimate)
Log P1.190

Safety & Handling

Warning
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H316Causes mild skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H360May damage fertility or the unborn child
H370Causes damage to organs
H371May cause damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P403Store in a well-ventilated place.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P316Get emergency medical help immediately.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29182200
UN Number1851
Storage Class11 - Combustible Solids
WGK (Germany)1