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Amines REACH

Paracetamol

CAS Number
103-90-2
EC Number
203-157-5
Chemical Formula
C8H9NO2
Molecular Weight
151.16 g/mol

Description

Paracetamol (CAS 103-90-2 ), also known as APAP (acetaminophen), is a globally sourced active pharmaceutical ingredient used as an analgesic and antipyretic in finished dosage forms. It is one of the highest-volume OTC drug substances in the world. With established supply chains across regulated and emerging markets, it serves as a cornerstone of modern medicine. In pharmaceutical manufacturing, it is the primary API in tablets, capsules, syrups, and effervescent formulations. These products target pain relief and fever reduction across various demographics. Pediatric liquid formulations represent a distinct high-demand segment, requiring specific particle size and solubility profiles that influence grade selection. It is also compounded into combination products alongside antihistamines, decongestants, and caffeine for cold and flu preparations. In personal care, it is evaluated as a UV stabilizer in select formulation research. Despite niche uses, pharmaceutical applications dominate procurement volume globally. The material is supplied as a white crystalline powder in standard and fine particle grades to meet diverse manufacturing needs. Recognized specifications include BP , USP , Ph.Eur. , and IP (Indian Pharmacopoeia). The Ph.Eur. and USP grades are most commonly required by regulated-market buyers for quality assurance. Bulk supply is available in fiber drums or multiwall bags for industrial use. GMP-certified manufacturing documentation is typically required for pharmaceutical procurement to ensure compliance with international safety standards. Contact us for supply of Paracetamol Request Quote

Other Names (Synonyms)

p-hydroxyphenolacetamide | p-hydroxyacetanilide | p-hydroxy-acetanilid | p-acetylaminophenol | p-acetaminophenol | p-acetamidophenol | N-acetyl-p-aminophenol4-hydroxyacetanilide | N-(4-hydroxyphenyl)acetamide | APAP

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point169-170.5 °C
Boiling Point500 °C
Density1.293 g/cm³ @ Temp: 21 °C
Flash Point11 °C
AppearanceWhite Solid
ColorWhite
Odorodorless
FormCrystals or Crystalline Powder
Water Solubility14 g/L (20 ºC)
Vapor Pressure0.008Pa at 25℃
Refractive Index1.5810 (rough estimate)
pH5.5-6.5 (H2O, 20℃)(saturated solution)
Log P1.098 at 25℃

Safety & Handling

Warning
GHS07· IrritantGHS09· EnvironmentGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
H370Causes damage to organs
H371May cause damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H401Toxic to aquatic life
H411Toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29242930
UN Number3077
ADR Class9
Packing GroupIII
WGK (Germany)1