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4-aminophenol

CAS Number
123-30-8
EC Number
204-616-2
Chemical Formula
C6H7NO
Molecular Weight
109.13 g/mol

Description

4-Aminophenol (CAS 123-30-8 ), also known as p-aminophenol, is a primary aromatic amine used as a key chemical intermediate in pharmaceutical synthesis and specialty chemical manufacturing. Its reactivity toward acylation and coupling reactions makes it a high-demand building block across multiple industrial sectors. In pharmaceuticals, it is the direct precursor to paracetamol. As one of the world's highest-volume analgesic APIs, it is a critical raw material for bulk drug manufacturers. Hair dye formulations rely on it as an oxidative colorant intermediate. It couples with other components to produce permanent color in consumer and professional products. It also functions as a photographic developer intermediate in printing and imaging chemistry. Controlled reduction reactions are essential to image formation in these processes. In rubber and polymer processing, it serves as an antioxidant precursor in the synthesis of stabilizer compounds. These compounds protect against thermal and oxidative degradation. 4-Aminophenol is supplied as an off-white to light brown crystalline powder for various industrial applications. Technical grade is the standard commercial form, with pharmaceutical-grade material available to meet API intermediate specifications including purity requirements aligned with USP standards. Material also meets Ph. Eur. standards for high-purity applications. Packaging typically ranges from small drums to bulk quantities depending on specific customer application requirements. Contact us for supply of 4-aminophenol Request Quote

Other Names (Synonyms)

p-hydroxyphenylamine | p-hydroxyaniline | 4-hydroxyaniline | 4-aminobenzenol | 4-amino-1-hydroxybenzene | 1-amino-4-hydroxybenzene | p-aminophenol | Phenol, 4-amino-

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point189.6-190.2 °C
Boiling Point284 °C
Density1.29
Flash Point189 °C
Appearanceo-Aminophenol appears as colorless needles or as white crystalline substance turning tan to brown on exposure to air.
ColorWhite to cream
FormCrystalline Powder
Water Solubility1.5 g/100 mL (20 ºC)
Vapor Pressure0.4 hPa (110 °C)
Refractive Index1.5444 (estimate)
Log P-0.09-0.04 at 25℃

Safety & Handling

Warning
GHS07· IrritantGHS08· Health HazardGHS09· Environment

Hazard Statements

H302Harmful if swallowed
H332Harmful if inhaled
H341Suspected of causing genetic defects
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H317May cause an allergic skin reaction
H320Causes eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H316Causes mild skin irritation
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure

Trade & Regulatory

HS Code28402090
UN Number2512
ADR Class6.1
Packing GroupIII
Storage Class6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany)3