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4-aminobenzoic acid

CAS Number
150-13-0
EC Number
205-753-0
Chemical Formula
C7H7NO2
Molecular Weight
137.14 g/mol

Description

4-Aminobenzoic acid (CAS 150-13-0 ), commonly known as PABA or para-aminobenzoic acid, is an aromatic amino acid derivative used as a key building block in pharmaceutical synthesis. Its bifunctional structure, carrying both an amine and a carboxylic acid group, makes it a reactive intermediate for producing dyes, UV absorbers, and active pharmaceutical ingredients. In pharmaceuticals, PABA serves as a precursor in the synthesis of local anesthetics such as benzocaine and procaine, as well as folate-class compounds for various medical uses. Textile and leather processors use it as an intermediate in azo dye production, where it contributes to colorfast, high-affinity dye systems for natural and synthetic fibers. In sunscreen and personal care formulations, PABA derivatives function as UV-B absorbing agents, though demand has shifted toward its ester forms in recent years. It also acts as a crosslinking and surface-modifying agent in specialty polymer and coating applications, providing versatility across multiple industrial chemical sectors. 4-Aminobenzoic acid is supplied as a white to off-white crystalline powder. Standard commercial grades include technical and pharmaceutical-grade material for diverse needs. The pharmaceutical supply conforms to USP and BP specifications. Bulk quantities are available for industrial synthesis, with smaller quantities offered for R&D use. Contact us for supply of 4-aminobenzoic acid Request Quote

Other Names (Synonyms)

para-aminobenzoic acid | p-carboxyphenylamine | p-carboxyaniline | p-aminobenzoic acid | gamma-aminobenzoic acid | aniline-4-carboxylic acid | 4-carboxyphenylamine | 4-carboxyaniline | PABA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point188.5 °C
Boiling Point200 °C @ Press: 10 Torr
Density1.367-1.395 g/cm³
Flash Point250 °C
AppearanceWhite to off white crystalline powder
ColorWhite to light yellow
OdorOdorless
FormCrystalline Powder
Water Solubility4.7 g/L (20 ºC)
Vapor Pressure0Pa at 25℃
Refractive Index1.5323 (estimate)
pH3.5 (5g/l, H2O, 20℃)
Log P0.96 at 25℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29224995
Storage Class11 - Combustible Solids
WGK (Germany)3