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4-biphenylcarboxylic acid

CAS Number
92-92-2
EC Number
202-203-1
Chemical Formula
C13H10O2
Molecular Weight
198.22 g/mol

Description

4-Biphenylcarboxylic acid (CAS 92-92-2 ), also known as 4-phenylbenzoic acid, is an aromatic carboxylic acid used as a building block and intermediate across pharmaceutical, polymer, and specialty chemical manufacturing. Its rigid biphenyl backbone makes it a preferred structural unit where defined molecular geometry is required in synthesis. In pharmaceutical manufacturing, it serves as a key intermediate in the synthesis of active pharmaceutical ingredients. It is particularly useful in the production of sartans and other biphenyl-containing drug compounds. Polymer chemists incorporate it into liquid crystal polymer formulations and high-performance polyesters where thermal stability is critical. Chain rigidity is a critical processing requirement for these materials. In coatings and adhesive systems, it functions as a crosslinking agent and pH modifier, contributing to formulation stability and film integrity. Specialty catalyst development also draws on this compound as a ligand precursor or co-catalyst component in organometallic reaction systems. 4-Biphenylcarboxylic acid is supplied as a white to off-white crystalline powder. Standard commercial offerings include technical grade and pharmaceutical-grade material, with purity specifications typically ranging from 98% to 99%+ by HPLC. Packaging is available in laboratory quantities through to bulk industrial volumes. These options support both R&D and commercial-scale procurement for global manufacturers. The material is handled according to strict quality protocols to ensure consistency across different production batches and applications. Contact us for supply of 4-biphenylcarboxylic acid Request Quote

Other Names (Synonyms)

4-Carboxylbiphenyl | [1,1'-Biphenyl]-4-carboxylic acid | 4-Phenylbenzoic acid | 4-Carboxybiphenyl | p-Phenylbenzoic acid | Para phenyl benzoic acid | 4-Diphenylcarboxylic acid | 36J7VPO67K

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point228 °C
Boiling Point295.53°C (rough estimate)
Density1.1184 (rough estimate)
Appearancewhite to light yellow crystal powder
ColorWhite to beige
FormCrystalline Powder
Water SolubilityInsoluble in water.
Refractive Index1.5954 (estimate)

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation

Precautionary Statements

P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29163900
Storage Class11 - Combustible Solids
WGK (Germany)1