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Cinchonine

CAS Number
118-10-5
EC Number
204-234-6
Chemical Formula
C19H22N2O
Molecular Weight
294.4 g/mol

Description

Cinchonine (CAS 118-10-5 ) is a natural cinchona bark alkaloid used across pharmaceutical, biotechnology, and personal care sectors. Commercially recognized as D-Cinchonine, it functions primarily as a chiral resolving agent. It serves as a biochemical tool compound in synthesis and research workflows. In pharmaceutical manufacturing, it resolves racemic mixtures to isolate enantiomerically pure active ingredients for production. This is a critical step in API production where chiral purity directly affects regulatory approval. Biotechnology researchers use it as a reference standard and chiral selector in chromatographic method development. Personal care formulators incorporate it into preservation systems where alkaloid-based antimicrobial activity supports product stability. It also serves research applications in asymmetric catalysis for development. Its quinuclidine-quinoline scaffold is used to develop organocatalyst systems. The material is supplied as a white to off-white crystalline powder available in reagent-grade and high-purity specifications. It is suited to pharmaceutical and analytical applications, with select suppliers offering material compliant with reference standard requirements. Packaging ranges from small research quantities to bulk orders. Industrial-scale chiral resolution processes utilize this compound for its reliable performance. The product meets rigorous industry expectations for consistency and chemical stability in various environments. Contact us for supply of Cinchonine Request Quote

Other Names (Synonyms)

D-Cinchonine | (9S)-Cinchonan-9-ol | Cinchonan-9-ol, (9S)- | (8R,9S)-Cinchonine | (+)-Cinconine | V43X79NZCD | Cinchonine Alkaloid

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point265 °C
Boiling Point436.16°C (rough estimate)
Density1.0863 (rough estimate)
Appearancewhite to light yellow crystal powde
ColorWhite to light beige
FormMicro-Crystalline Powder
Water SolubilityInsoluble
Vapor Pressure0Pa at 25℃
Refractive Index223 ° (C=0.5, EtOH)
pH9.0 (0.25g/l, H2O, 20℃)(as aqueous solution)
Log P2.82 at 25℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H302
H302
H317
H317
H332H332

Precautionary Statements

P261
P261
P264
P264
P270
P270
P271
P271
P272
P272
P280
P280
P317
P317
P321
P321
P330
P330
P501
P501
P317
P317
P352
P352
P340
P340
P317
P317
P364

Trade & Regulatory

HS Code29339900
WGK (Germany)3