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Quinine hydrochloride dihydrate

CAS Number
6119-47-7
EC Number
205-001-1
Chemical Formula
C20H24N2O2.ClH.2H2O
Molecular Weight
396.9 g/mol

Description

Quinine hydrochloride dihydrate (CAS 6119-47-7 ), commonly referenced as Quinine HCl Dihydrate in pharmaceutical procurement, is the water-soluble hydrochloride salt form of quinine supplied in its stable dihydrate state. It functions as an antimalarial active and bitter-tasting agent across pharmaceutical and personal care manufacturing. In pharmaceutical manufacturing, it serves as an active pharmaceutical ingredient in antimalarial formulations. Its hydrochloride salt form offers improved aqueous solubility over quinine sulfate for injectable and oral dosage development. Beverage and flavoring applications utilize its intensely bitter profile to standardize bitterness. It is used in tonic formulations and reference standards. In personal care and cosmetic formulations, it is incorporated into scalp treatments and hair care products targeting hair loss and scalp conditioning. QA and analytical laboratories source it as a reference standard for UV fluorescence calibration and spectrophotometric method validation. Quinine hydrochloride dihydrate is available as a white to off-white crystalline powder. It is supplied in pharmaceutical-grade specifications aligned with BP and Ph. Eur. monographs, supporting GMP-compliant manufacturing environments. Packaging ranges from small quantities to bulk quantities. Contact us for supply of Quinine hydrochloride dihydrate Request Quote

Other Names (Synonyms)

Quinine HCl Dihydrate | Cinchonan-9-ol, 6'-methoxy-, monohydrochloride, dihydrate, (8a,9R)- | Quinidine Hydrochloride Dihydrate | Cinchonan-9-ol, 6′-methoxy-, hydrochloride, hydrate (1:1:2), (8α,9R)- | Cinchonan-9-ol, 6′-methoxy-, monohydrochloride, dihydrate, (8α,9R)-

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point123 °C (approx)
Flash Point122 °C
Appearancewhite to light yellow crystal powde
ColorWhite to off-white
Odorodorless
FormCrystalline Powder or Silky Needles
Water SolubilitySparingly soluble in water.(0.26 g/L) (25°C),
Refractive Index-250 ° (C=2, EtOH)
pH6.0 (10g/l, H2O, 20℃)

Safety & Handling

Warning
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H302
H302
H317
H317
H332
H332
H334H334

Precautionary Statements

P233
P233
P260
P260
P261
P261
P264
P264
P270
P270
P271
P271
P272
P272
P280
P280
P284
P284
P317
P317
P321
P321
P330
P330
P403
P403
P501
P501
P317
P317
P352
P352
P340
P340
P317
P317
P316
P316
P364

Trade & Regulatory

HS Code29334900
Storage Class11 - Combustible Solids
WGK (Germany)3