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Quinine hydrochloride

CAS Number
130-89-2
EC Number
205-001-1
Chemical Formula
C20H24N2O2.ClH
Molecular Weight
360.9 g/mol

Description

Quinine hydrochloride (CAS 130-89-2 ), also known as Quinine HCl, is the salt form of quinine derived from cinchona bark alkaloids. It is used primarily in pharmaceutical manufacturing as an active ingredient and intermediate. Its water solubility makes it the preferred form over quinine base for oral and injectable dosage development. In pharmaceutical manufacturing, Quinine HCl is formulated into tablets, capsules, and injectable solutions. These formulations target malaria treatment and fever management across various clinical settings. The food and beverage industry sources it under FEMA 2976 as a bittering agent in tonic waters and carbonated soft drinks. Precise dosing controls the characteristic bitter taste profile required for these beverages. It also appears in topical and oral formulations developed for nocturnal leg cramp management in select regulated markets. Compounding pharmacies use it as a starting material when preparing customized dosage forms requiring defined quinine salt concentrations. Quinine hydrochloride is supplied as a white crystalline powder in anhydrous form. Standard grades include USP , BP , and Ph. Eur. , supporting procurement for regulated pharmaceutical and food applications. Bulk quantities are available for industrial buyers and R&D customers. Contact us for supply of Quinine hydrochloride Request Quote

Other Names (Synonyms)

quinine hydrochloride anhydrous | Quinine HCl | Quinine muriate | Quinine monohydrochloride | Chininum muriaticum | Quinini hydrochloridum | HCl

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point159 °C
Density1.1206 (rough estimate)
ColorWhite
FormSolid
Water Solubility549.7mg/L(25 ºC)
Refractive Index1.5400 (estimate)
Log P3.496 (est)

Safety & Handling

Warning
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H302
H302
H312
H312
H317
H317
H332
H332
H334H334

Precautionary Statements

P233
P233
P260
P260
P261
P261
P264
P264
P270
P270
P271
P271
P272
P272
P280
P280
P284
P284
P317
P317
P321
P321
P330
P330
P403
P403
P501
P501
P317
P317
P352
P352
P340
P340
P317
P317
P316
P316
P364

Trade & Regulatory

HS Code29392000