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Chloroquine

CAS Number
54-05-7
EC Number
200-191-2
Chemical Formula
C18H26ClN3
Molecular Weight
319.9 g/mol

Description

Chloroquine (CAS 54-05-7 ) is a synthetic 4-aminoquinoline compound established as a reference pharmaceutical active ingredient and research chemical. It serves as a primary building block and analytical reference standard in drug development. Supplied as the base or phosphate salt form, it is essential for manufacturing workflows. Pharmaceutical manufacturers use it as an active pharmaceutical ingredient in the production of finished dosage forms. These forms primarily include tablets and oral solutions targeting parasitic indications. Research institutions and contract development organizations source it as a reference standard for analytical method validation. It is also utilized for bioequivalence studies and pharmacokinetic assays. In drug discovery programs, it functions as a scaffold compound for synthesizing novel quinoline-based derivatives under investigation. Formulators working on generic drug development use it as a comparator substance. This application is critical during formulation optimization and stability testing protocols to ensure product efficacy and safety. The material is available as a free base or, more commonly, as Chloroquine phosphate. This is the predominant commercial salt form used in finished pharmaceutical production across the global industry. Standard grades include USP , BP , and Ph.Eur. specifications for compliance. Research-grade material is also supplied for non-GMP laboratory applications and experimental chemical synthesis. Packaging ranges from small quantities for reference use to bulk quantities supporting commercial API manufacturing. This flexibility ensures that both laboratory and industrial requirements are met efficiently. Contact us for supply of Chloroquine Request Quote

Other Names (Synonyms)

N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine | 7-chloro-4-{[4-(diethylamino)-1-methylbutyl]amino}quinolinium | (RS)-chloroquine | Aralen | Artrichin | Bipiquin | 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl- | Quinoline, 7-chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]-

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point87-92 °C
Boiling Point230-235 °C @ Press: 3-4 Torr
Density1.0500 (rough estimate)
Appearancesolid
ColorWhite to Light Brown
FormSolid
Refractive Index1.6010 (estimate)

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H302Harmful if swallowed

Precautionary Statements

P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P330Rinse mouth.
P501Dispose of contents/container in accordance with local regulations.
P317Get emergency medical help.