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Isoquinoline

CAS Number
119-65-3
EC Number
204-341-8
Chemical Formula
C9H7N
Molecular Weight
129.16 g/mol

Description

Isoquinoline (CAS 119-65-3 ), also known commercially as leucoline, is a bicyclic nitrogen-containing aromatic compound sourced primarily from coal tar fractions. Assigned FEMA 2978 , it functions as a flavoring agent and fragrance intermediate. In flavor formulation, this compound contributes characteristic coal tar and quinoline-like nuances used at trace levels in complex flavor systems. It is particularly effective in targeting savory and roasted profiles for food products. Fragrance manufacturers use it as a building block for synthesizing more complex aroma compounds, particularly in oriental and tobacco-type compositions. It provides a unique structural base for high-end perfumery applications. In personal care, it is evaluated for preservation-enhancing properties within multi-functional formulations where antimicrobial support is needed. This dual-purpose functionality makes it a versatile choice for cosmetic chemists. Food-grade applications are governed by FEMA status, positioning it for use in approved flavoring contexts. Documentation of permitted use is a standard procurement requirement for industrial food manufacturing and safety compliance. The product is supplied as a liquid or low-melting solid, depending on ambient temperature and purity level. Standard commercial grades are available at purities ranging from technical to high-purity levels of 98% or higher. High-purity grades are specifically required for flavor and fragrance end uses to ensure consistent sensory profiles. Packaging typically ranges from small laboratory quantities up to drum-scale volumes for industrial buyers. Contact us for supply of Isoquinoline Request Quote

Other Names (Synonyms)

2-Benzazine | 2-Azanaphthalene | Leucoline | beta-Quinoline | Benzo[c]pyridine | 3,4-Benzopyridine

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point26.47 °C
Boiling Point242.6-244.0 °C
Density1.096 g/cm³ @ Temp: 204 °C
Flash Point225 °F
AppearanceLIGHT BROWN LOW MELTLING SOLID
ColorLight brown
Odorat 0.10 % in triacetin. sweet balsam herbal benzaldehyde anise
FormLow Melting Solid
Water Solubilitypractically insoluble
Vapor Pressure5Pa at 20℃
Refractive Indexn 20/D 1.623(lit.)
pH7.5 (5g/l, H2O, 20℃)
Log P2.08

Safety & Handling

Danger
GHS06· ToxicGHS07· Irritant

Hazard Statements

H302Harmful if swallowed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H402Harmful to aquatic life
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off immediately all contaminated clothing and wash it before reuse.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29334900
UN Number2811
ADR Class6.1
Packing GroupIII
WGK (Germany)2