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3-Bromoquinoline

CAS Number
5332-24-1
EC Number
226-237-1
Chemical Formula
C9H6BrN
Molecular Weight
208.05 g/mol

Description

3-Bromoquinoline (CAS 5332-24-1 ) is a halogenated heterocyclic building block used primarily in pharmaceutical synthesis and specialty chemical manufacturing. The bromine substituent at the 3-position makes it a reactive intermediate for cross-coupling reactions. This functionality enables the efficient construction of more complex quinoline-based structures. In pharmaceutical development, it serves as a key intermediate for synthesizing active pharmaceutical ingredients and drug candidates. This is particularly relevant where quinoline scaffolds are required for biological activity. Polymer and plastics manufacturers incorporate brominated quinoline derivatives into flame retardant formulations for industrial use. In these applications, the halogen content contributes to combustion suppression in finished materials. In textile and paper treatment chemistries, it functions as a precursor to preservation and stabilization compounds. These compounds protect substrates from degradation over time. Research and fine chemical producers also source it for producing ligands, dyes, and specialty reagents where a functionalized quinoline core is the starting point. 3-Bromoquinoline is supplied as a liquid or low-melting solid, typically at purities of 97% or higher for synthetic and research applications. Technical and high-purity grades are available to meet specific requirements. These grades support pharmaceutical intermediates manufacturing and specialty chemical production. Packaging ranges from small quantities for R&D use to bulk quantities for industrial-scale synthesis programs. Contact us for supply of 3-Bromoquinoline Request Quote

Other Names (Synonyms)

Quinoline, 3-bromo- | AI3-16560 | RefChem:93267 | Quinolin-3-yl bromide | DI-SEC-BUTYLAMINE

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point13.3 °C
Boiling Point103-105 °C @ Press: 1.5 Torr
Density1.533 g/mL at 25 °C(lit.)
Flash Point>230 °F
Appearancecolorless to light yellow liquid
ColorClear colorless to yellow
FormLiquid
Water Solubility103mg/L at 25℃
Vapor Pressure0.196Pa at 25℃
Refractive Indexn 20/D 1.664(lit.)
Log P3.03

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29334900
UN Number2810
Storage Class10 - Combustible liquids
WGK (Germany)3