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2-bromothiophene

CAS Number
1003-09-4
EC Number
213-699-4
Chemical Formula
C4H3BrS
Molecular Weight
163.04 g/mol

Description

2-Bromothiophene (CAS 1003-09-4 ), also known as 2-thienyl bromide, is a halogenated heterocyclic building block used across pharmaceutical synthesis and specialty chemical manufacturing. It serves as a reactive intermediate for introducing the thiophene scaffold into complex organic molecules through cross-coupling and metal-catalyzed reactions in various industrial settings. In pharmaceutical development, this compound is a key precursor for active pharmaceutical ingredients where the thiophene ring is a core structural element, including antifungal and antihistamine compounds. Flavor and fragrance chemists use it to access thienyl-containing aroma compounds through further functionalization. It participates in Suzuki, Kumada, and Negishi coupling reactions for advanced intermediates. Specialty chemical producers also use it as a starting material for liquid crystal components and conducting polymer monomers, supporting innovation in agrochemical and materials science applications. The product is supplied as a liquid in standard commercial quantities ranging from laboratory-scale packaging to bulk drums. Technical and high-purity grades are available for diverse industrial needs. Purity specifications are typically at 97–99%+ to meet the demands of pharmaceutical and fine chemical synthesis. Buyers should confirm grade documentation and certificate of analysis requirements. For those sourcing for GMP-regulated processes, ensure the material meets necessary quality standards. Proper handling and storage protocols must be followed to maintain the integrity of the chemical. Contact us for supply of 2-bromothiophene Request Quote

Other Names (Synonyms)

2-thienyl bromide | Thiophene, 2-bromo- | GFF929NUW7 | Monobromothiophene.

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point<25 °C
Boiling Point53-56 °C @ Press: 18 Torr
Density1.6284 g/cm³ @ Temp: 20 °C
Flash Point140 °F
Appearancecolorless to light yellow liqui
ColorClear colorless to slightly brownish
FormLiquid
Water SolubilityIMMISCIBLE
Refractive Indexn 20/D 1.586(lit.)

Safety & Handling

Danger
GHS02· FlammableGHS05· CorrosiveGHS06· ToxicGHS07· Irritant

Hazard Statements

H226
H226
H300
H300
H301
H301
H310
H310
H315
H315
H318
H318
H319
H319
H330H330

Precautionary Statements

P210
P210
P233
P233
P240
P240
P241
P241
P242
P242
P243
P243
P260
P260
P262
P262
P264
P264
P270
P270
P271
P271
P280
P280
P284
P284
P316
P316
P317
P317
P320
P320
P321
P321
P330
P330
P405
P405
P501
P501
P265
P265
P316
P316
P352
P352
P340
P340
P317
P317
P317
P317
P364
P364
P364
P364
P378
P378
P233
P233
P235
P235
P353
P353
P338
P338
P338

Trade & Regulatory

HS Code29349990
UN Number2929
ADR Class6.1
Packing GroupII
Storage Class3 - Flammable liquids
WGK (Germany)3