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Diphenylmethane diisocyanate

CAS Number
101-68-8
EC Number
202-966-0
Chemical Formula
C15H10N2O2
Molecular Weight
250.25 g/mol

Description

Diphenylmethane diisocyanate ( CAS 101-68-8 ), commonly known as MDI, is a core isocyanate monomer used to produce polyurethane polymers across rigid, flexible, and elastomeric applications. It reacts with polyols to build polymer chains, enabling manufacturers to engineer foam density, hardness, and durability to precise specifications for various industrial uses. In building and construction, MDI is the primary reactant in rigid polyurethane and polyisocyanurate insulation panels, where it delivers high thermal resistance in thin cross-sections. Automotive manufacturers rely on MDI-based systems for structural foam components, seating, headliners, and interior trim parts requiring consistent load-bearing performance and safety. In adhesives and sealants, MDI functions as a crosslinker that bonds dissimilar substrates including wood, metal, and composites under demanding mechanical and environmental conditions. Coatings and elastomer formulators use MDI to produce abrasion-resistant surfaces for industrial flooring, rollers, and protective linings that must withstand heavy daily wear. MDI is supplied as a liquid in several commercially distinct forms: pure 4,4'-MDI, polymeric MDI (pMDI), and modified MDI variants including prepolymers and carbodiimide-modified grades. Polymeric MDI is the dominant commercial form for foam applications, while pure MDI grades serve elastomer formulators requiring tighter isomer control for high-end manufacturing. Contact us for supply of Diphenylmethane diisocyanate Request Quote

Other Names (Synonyms)

4,4'-methylenediphenyldiisocyanate | Methylene diphenyl diisocyanate (mdi) | 1-isocyanato-4-[(4-isocyanatophenyl)methyl]benzene | Methylene diphenyl diisocyanate | MDI

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point37 °C
Boiling Point196 °C @ Press: 5 Torr
Density1.197 g/cm³ @ Temp: 70 °C
Flash Point196 °C
AppearanceMDI is a white to light-yellow, odorless flakes. A liquid above 37C.
ColorWhite to Almost white
Formneat
Water Solubilitydecomposes
Vapor Pressure0.066 hPa (20 °C)
Refractive Index1.5906 (estimate)

Safety & Handling

Danger
GHS07· IrritantGHS08· Health HazardGHS06· Toxic

Hazard Statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H320Causes eye irritation
H330Fatal if inhaled
H332Harmful if inhaled
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H351Suspected of causing cancer
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P403Store in a well-ventilated place.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P316Get emergency medical help immediately.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29291090
Storage Class11 - Combustible Solids
WGK (Germany)1