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3-cyanopyridine

CAS Number
100-54-9
EC Number
202-863-0
Chemical Formula
C6H4N2
Molecular Weight
104.11 g/mol

Description

3-Cyanopyridine (CAS 100-54-9 ), also known as nicotinic acid nitrile and commonly abbreviated as 3-CP, is a pyridine-based nitrile intermediate used across pharmaceutical synthesis and agrochemical manufacturing. It serves primarily as a building block for constructing more complex heterocyclic structures, including vitamin B3 derivatives and active pharmaceutical ingredients. In pharmaceutical manufacturing, 3-CP is a direct precursor to nicotinamide. Nicotinic acid is also produced from this intermediate at industrial scale through controlled hydrolysis. Agrochemical producers use it as an intermediate in synthesizing pyridine-based pesticides and fungicides. The nitrile group enables selective downstream functionalization for various specialty chemical applications. In flavor chemistry, nicotinic acid nitrile contributes to the production of compounds with roasted and meaty flavor profiles. These profiles are highly relevant to food ingredient formulation and development. Biotechnology and life sciences applications include its use as a reagent in catalyst development and as a substrate in enzymatic hydrolysis research. This research often targets nitrile hydratase activity for advanced chemical processing. 3-Cyanopyridine is supplied as a white to off-white crystalline solid available in technical and pharmaceutical-grade specifications. Purity levels typically range from 98% to 99%+ depending on the intended application. Packaging options range from kilogram-scale laboratory quantities to multi-tonne bulk supply for industrial users. Contact us for supply of 3-cyanopyridine Request Quote

Other Names (Synonyms)

3-azabenzonitrile | 3-PYRIDINECARBONITRILE | Nicotinic acid nitrile | 3-Pyridinenitrile | 3-Pyridylcarbonitrile | Nitryl kwasu nikotynowego | 3-Pyridinecarboxylic acid, nitrile | Pyridine-3-carbonitrile | 3-CP

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point51 °C
Boiling Point206.9 °C
Density1.1590 g/cm³ @ Temp: 25 °C
Flash Point184 °F
AppearanceThe cyanopyridines are as follows: 2-cyano-: A white to tan liquid or solid. Almond odor. Boiling point=2213℃
freezing/melting point=27℃
flash point=89℃ . 3-cyano-a colorless liquid or gray crystal- line solid.
ColorColorless or white to yellow
FormCrystalline Mass, Crystals or Chunks
Water Solubility140 g/L (20 ºC)
Refractive Index1.5242 (estimate)

Safety & Handling

Warning
GHS05· CorrosiveGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H302
H302
H315
H315
H318
H318
H319
H319
H335
H335
H371
H371
H373H373

Precautionary Statements

P260
P260
P261
P261
P264
P264
P270
P270
P271
P271
P280
P280
P317
P317
P319
P319
P321
P321
P330
P330
P405
P405
P501
P501
P265
P265
P317
P317
P352
P352
P340
P340
P316
P316
P317
P317
P317
P317
P364
P364
P233
P233
P338
P338
P338

Trade & Regulatory

HS Code29333999
Storage Class11 - Combustible Solids
WGK (Germany)3