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4-cyanopyridine

CAS Number
100-48-1
EC Number
202-856-7
Chemical Formula
C6H4N2
Molecular Weight
104.11 g/mol

Description

4-Cyanopyridine (CAS 100-48-1 ), also known as isonicotinic acid nitrile and abbreviated as 4-CP, is a pyridine-based nitrile building block used across pharmaceutical synthesis and specialty chemical manufacturing. It functions primarily as a reactive intermediate, enabling the construction of more complex heterocyclic structures through its dual nitrile and pyridine functionalities in various chemical processes. In pharmaceutical manufacturing, 4-CP is a key precursor in the synthesis of antifungal agents, antivirals, and other nitrogen-containing active pharmaceutical ingredients for the global market. It is used in the production of ligands and coordination complexes that serve as catalysts or catalyst precursors in organometallic chemistry and advanced material science applications. Agrochemical formulators use it as a building block for pyridine-derived herbicides and fungicides. In flavor chemistry, isonicotinic acid nitrile contributes to select fragrance and flavor compound synthesis. This is particularly useful where pyridine-ring structures are required. 4-Cyanopyridine is supplied as a white to off-white crystalline solid for industrial and laboratory use. Standard commercial grades include technical and high-purity specifications suitable for pharmaceutical intermediate and research applications. Packaging typically ranges from kilogram-scale to bulk orders. Our supply chain ensures consistent quality for multi-hundred kilogram bulk orders for industrial synthesis. We maintain strict adherence to safety and handling protocols for all chemical shipments. Contact us for supply of 4-cyanopyridine Request Quote

Other Names (Synonyms)

4-Pyridinecarbonitrile | pyridine-4-carbonitrile | Isonicotinic acid nitrile | BY3226D010 | γ-Cyanopyridine | p-Cyanopyridine | 4-CP

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point79 °C
Boiling Point78 °C @ Press: 6 Torr
Density1.1145 (rough estimate)
Flash Point88 °C
AppearanceThe cyanopyridines are as follows: 2-cyano-: A white to tan liquid or solid. Almond odor. Boiling point=2213℃
freezing/melting point=27℃
flash point=89℃ . 3-cyano-a colorless liquid or gray crystal- line solid.
ColorWhite to off-white
FormCrystals or Powder
Water Solubility3.2 g/100ml (16.4 ºC)
Vapor Pressure41.9Pa at 25℃
Refractive Index1.5242 (estimate)
Log P0.46 at 25℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H302
H302
H312
H312
H319
H319
H332H332

Precautionary Statements

P261
P261
P264
P264
P270
P270
P271
P271
P280
P280
P317
P317
P321
P321
P330
P330
P501
P501
P265
P265
P317
P317
P352
P352
P340
P340
P317
P317
P364
P364
P338

Trade & Regulatory

HS Code29333999
Storage Class11 - Combustible Solids
WGK (Germany)3