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Amines REACH

Pyrrolidine

CAS Number
123-75-1
EC Number
204-648-7
Chemical Formula
C4H9N
Molecular Weight
71.12 g/mol

Description

Pyrrolidine (CAS 123-75-1 ), also known as Azolidine, is a saturated five-membered nitrogen heterocycle used as a flavoring agent and chemical intermediate across food, pharmaceutical, and personal care industries. Assigned FEMA 3523 , it functions as a building block for synthesizing active ingredients and flavor compounds rather than as a finished additive in its own right for most industrial applications. In food and flavor manufacturing, it is used to produce thermally derived flavor compounds that contribute roasted, grain, and savory notes to processed foods and beverages during the production cycle. Pharmaceutical formulators rely on it as a key synthetic intermediate for APIs, where the pyrrolidine ring is incorporated into drug candidates targeting a range of therapeutic categories and medical needs. In personal care, it supports the synthesis of conditioning agents and specialty amines used in hair and skin formulations. Agrochemical producers also use it as an intermediate in fungicide and pesticide synthesis. Pyrrolidine is supplied as a colorless to pale yellow liquid in standard drum and IBC packaging. Technical and reagent grades are the most commonly available for industrial and laboratory procurement needs. High-purity pharmaceutical-grade material is offered for API synthesis applications. Buyers should confirm purity specifications and moisture content with suppliers, as grade requirements vary significantly by end use. Material quality is often verified against internal manufacturer specifications or recognized standards such as USP , Ph.Eur. , BP , EP , FCC , or ACS depending on the specific grade and application. Contact us for supply of Pyrrolidine Request Quote

Other Names (Synonyms)

Azolidine | Prolamine | 1-Azacyclopentane | Pyrrole, tetrahydro- | 2-Imidazolidone

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-63 °C
Boiling Point86.71 °C
Density0.8520 g/cm³ @ Temp: 22.5 °C
Flash Point37 °F
Appearancecolourless to pale yellow liquid with a penetrating
ColorColorless to Almost colorless
Odorat 0.10 % in propylene glycol. ammoniacal animal egg amine
FormLiquid
Water SolubilityMiscible with alcohol, ether, chloroform and water.
Vapor Pressure128 mm Hg ( 39 °C)
Refractive Indexn 20/D 1.443(lit.)
pH12.9 (100g/l, H2O, 20℃)
Log P0.22 at 25℃

Safety & Handling

Danger
GHS02· FlammableGHS05· CorrosiveGHS07· IrritantGHS06· ToxicGHS08· Health Hazard

Hazard Statements

H225Highly Flammable liquid and vapor
H301Toxic if swallowed
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H330Fatal if inhaled
H332Harmful if inhaled
H370Causes damage to organs

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29339900
UN Number1922
ADR Class3
Packing GroupII
Storage Class3 - Flammable liquids
WGK (Germany)2