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2-methylpyridine

CAS Number
109-06-8
EC Number
203-643-7
Chemical Formula
C6H7N
Molecular Weight
93.13 g/mol

Description

2-Methylpyridine (CAS 109-06-8 ), commercially known as alpha-picoline, is a nitrogen-containing heterocyclic compound used as a key building block in pharmaceutical synthesis, agrochemical production, and specialty chemical manufacturing. It functions primarily as a chemical intermediate, enabling the construction of more complex active molecules across multiple regulated industries. In pharmaceutical manufacturing, alpha-picoline serves as a precursor to vinylpyridine derivatives. It is essential for the production of antihistamines and vitamins including B6 and melatonin-related compounds. Agrochemical producers use it to synthesize herbicides and insecticides, particularly chloropyrifos-related intermediates. In flavor and fragrance applications, 2-picoline contributes to the synthesis of specific aroma compounds where its reactivity at the methyl group is commercially exploited. It also functions as a catalyst or co-solvent. The material is utilized in select organic synthesis processes, including resin and polymer production. 2-Methylpyridine is supplied as a liquid in standard industrial drum and IBC quantities, with bulk tanker options available. Technical grade is the predominant commercial specification, with purity levels typically at 99% or higher confirmed by GC analysis. Pharmaceutical-grade material meeting relevant compendial standards is available for regulated synthesis. Select manufacturers provide material that adheres to USP or BP standards for specific applications. This ensures high-quality performance across diverse industrial sectors and chemical manufacturing processes. Contact us for supply of 2-methylpyridine Request Quote

Other Names (Synonyms)

alpha-picoline | a-Picoline | 2-Picoline | o-Picoline | Pyridine, 2-methyl- | alpha-Methylpyridine | o-Methylpyridine | PICOLINE, ALPHA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-70 °C
Boiling Point128-129 °C
Density0.9443 g/cm³ @ Temp: 20 °C
Flash Point79 °F
AppearancePicolines are colorless liquids. Strong, unpleasant, pyridine-like odor.“Picoline” is often used as mixed isomers.
ColorClear pale yellow
OdorUnpleasant
FormLiquid
Water SolubilityMISCIBLE
Vapor Pressure10 mm Hg ( 24.4 °C)
Refractive Indexn 20/D 1.500(lit.)
pH8.5 (100g/l, H2O, 20℃)
Log P1.11 at 20℃

Safety & Handling

Danger
GHS02· FlammableGHS07· IrritantGHS05· CorrosiveGHS06· ToxicGHS08· Health Hazard

Hazard Statements

H226
H226
H302
H302
H311
H311
H312
H312
H314
H314
H318
H318
H319
H319
H331
H331
H332
H332
H335
H335
H361
H361
H370
H370
H371
H371
H372H372

Precautionary Statements

P203
P203
P210
P210
P233
P233
P240
P240
P241
P241
P242
P242
P243
P243
P260
P260
P261
P261
P262
P262
P264
P264
P270
P270
P271
P271
P280
P280
P316
P316
P317
P317
P318
P318
P319
P319
P321
P321
P330
P330
P363
P363
P405
P405
P501
P501
P265
P265
P317
P317
P352
P352
P340
P340
P316
P316
P317
P317
P364
P364
P364
P364
P378
P378
P233
P233
P235
P235
P331
P331
P354
P354
P353
P353
P338
P338
P338

Trade & Regulatory

HS Code29333999
UN Number2313
ADR Class3
Packing GroupIII
Storage Class3 - Flammable liquids
WGK (Germany)1