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2-chloronicotinic acid

CAS Number
2942-59-8
EC Number
220-937-0
Chemical Formula
C6H4ClNO2
Molecular Weight
157.55 g/mol

Description

2-Chloronicotinic acid (CAS 2942-59-8 ) is a halogenated pyridinecarboxylic acid used primarily as a building block in pharmaceutical synthesis and agrochemical manufacturing. Its reactive chloro and carboxylic acid groups make it a reliable intermediate for constructing more complex heterocyclic structures across multiple industries and chemical research applications. In pharmaceutical development, it serves as a key intermediate in the synthesis of active pharmaceutical ingredients, particularly antiviral, antibacterial, and CNS-targeted compounds. Agrochemical formulators use it to produce herbicide and fungicide active substances, where the chloropyridine scaffold contributes significantly to the final biological activity. In specialty chemical manufacturing, it functions as a precursor for flame retardant additives and catalyst components used in various types of polymer processing and stabilization. Personal care and textile applications draw on its reactivity for surface modification agents and preservation chemistry in formulated products requiring specific chemical stability. This product is supplied as a white to off-white crystalline powder. Standard commercial offerings include technical grade and high-purity grades suitable for pharmaceutical intermediate use. Purity levels are typically at 98% or above confirmed by HPLC. Packaging ranges from small quantities for R&D procurement to bulk quantities for industrial-scale synthesis. Contact us for supply of 2-chloronicotinic acid Request Quote

Other Names (Synonyms)

2-Chloropyridine-3-carboxylic acid | 2-Chloro-3-pyridinecarboxylic acid | 3-Pyridinecarboxylic acid, 2-chloro- | Nicotinic acid, 2-chloro- | 3-Carboxy-2-chloropyridine | CNIS

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point194.00 °C
Boiling Point316.8±22.0 °C(Predicted)
Density1.470±0.06 g/cm3(Predicted)
AppearanceWhite to cream powder
ColorWhite to cream
OdorPungent odor
FormPowder
Log P0.988

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29333999
Storage Class11 - Combustible Solids
WGK (Germany)3