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Benzonitrile

CAS Number
100-47-0
EC Number
202-855-7
Chemical Formula
C7H5N
Molecular Weight
103.12 g/mol

Description

Benzonitrile (CAS 100-47-0 ), also known as phenyl cyanide, is an aromatic nitrile solvent and chemical intermediate used across pharmaceutical synthesis, flavor chemistry, and catalyst manufacturing. Its role is primarily as a reactive building block and polar aprotic solvent in multi-step organic synthesis. In pharmaceutical manufacturing, it serves as a key intermediate in the synthesis of active pharmaceutical ingredients. This is particularly important where nitrile-to-amine or nitrile-to-amide transformations are required. Flavor and fragrance formulators use it as a precursor to benzylamine derivatives and aromatic aroma compounds. These compounds are frequently found in finished flavor blends. In catalyst development, it acts as a ligand precursor and stabilizing agent in transition metal catalyst systems, including palladium-based catalysts. Specialty chemical producers also employ it as a solvent in electrochemical applications and high-polarity reaction media. It is often used where conventional solvents are unsuitable for specific chemical reactions. The product is supplied as a clear liquid in standard packaging ranging from laboratory quantities to bulk drums and IBC containers. Technical grade is the most common commercial specification available. High-purity grades of 99% or greater are available for pharmaceutical and catalyst applications. Buyers sourcing for regulated end uses should confirm purity certificates and residual impurity profiles with suppliers. Contact us for supply of Benzonitrile Request Quote

Other Names (Synonyms)

C6H5-CN | benzoic acid nitrile | Phenyl cyanide | Benzene, cyano-

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-13.1 °C
Boiling Point190.7 °C @ Press: 760 Torr
Density1.010 g/cm³ @ Temp: 15 °C
Flash Point161 °F
AppearanceBezonitrile is a colorless, oily liquid. It has an almond odor.
ColorClear colorless to slightly yellow
OdorAlmond-like.
FormLiquid
Water Solubility10 g/L (100 ºC)
Vapor Pressure1 hPa at 20 °C
Refractive Indexn 20/D 1.528(lit.)
Log P1.5 at 20℃

Safety & Handling

Warning
GHS07· IrritantGHS06· ToxicGHS08· Health Hazard

Hazard Statements

H227Combustible liquid
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
H370Causes damage to organs
H371May cause damage to organs
H373May causes damage to organs through prolonged or repeated exposure
H402Harmful to aquatic life

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P403Store in a well-ventilated place.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29269090
UN Number2224
ADR Class6.1
Packing GroupII
Storage Class6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany)2