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Benzoyl chloride

CAS Number
98-88-4
EC Number
202-710-8
Chemical Formula
C7H5ClO
Molecular Weight
140.56 g/mol

Description

Benzoyl chloride (CAS 98-88-4 ) is a high-reactivity acylating agent used across pharmaceutical synthesis, agrochemical manufacturing, and specialty chemical production. It introduces the benzoyl group into target molecules, enabling the construction of esters, amides, and anhydrides at industrial scale. In pharmaceutical manufacturing, it serves as a key intermediate in the synthesis of active ingredients, including analgesics, antimicrobials, and UV-absorbing compounds used in topical formulations. Cosmetic chemists use it to produce benzoate esters and benzoyl peroxide precursors. These precursors function as preservatives and antimicrobial agents in personal care products. It is also employed in the production of dyes, resins, and agrochemical intermediates where controlled benzoylation is required for specific chemical reactions. In laboratory and biotech settings, it acts as a derivatizing agent for analytical workflows, enabling detection and characterization of alcohols and amines. This versatility makes it an essential component for research and development across various scientific disciplines. Benzoyl chloride is supplied as a colorless to pale yellow liquid in standard packaging ranging from small reagent quantities to bulk drums and ISO tanks. Technical and reagent grades are the most commercially available options for industrial buyers. Purity specifications typically range from 98% to 99% or higher depending on the specific grade required. Buyers sourcing for pharmaceutical applications should confirm compliance with relevant pharmacopoeial or GMP documentation requirements for their supply chain. Standard quality benchmarks often include USP , BP , or EP standards depending on the region of use. Ensuring these quality standards are met is critical for maintaining the integrity of the final chemical or pharmaceutical product being manufactured. Contact us for supply of Benzoyl chloride Request Quote

Other Names (Synonyms)

Benzenecarbonyl chloride | Benzoic acid, chloride | alpha-Chlorobenzaldehyde | Benzaldehyde, alpha-chloro- | VTY8706W36 | Benzaldehyde, α-chloro- | Phenylcarbonyl chloride

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-1.0 °C
Boiling Point197.2 °C @ Press: 760 Torr
Density1.2070 g/cm³ @ Temp: 25 °C
Flash Point156 °F
AppearanceBenzoyl chloride is a colorless to slight brown liquid with a strong, penetrating odor.
ColorClear
OdorPungent characteristic.
FormLiquid
Water Solubilityreacts
Vapor Pressure1 mm Hg ( 32 °C)
Refractive Indexn 20/D 1.553(lit.)
pH2 (1g/l, H2O, 20℃)
Log P1.44 at 21℃ and pH6

Safety & Handling

Danger
GHS05· CorrosiveGHS07· IrritantGHS06· ToxicGHS08· Health HazardGHS09· Environment

Hazard Statements

H227Combustible liquid
H302Harmful if swallowed
H311Toxic in contact with skin
H312Harmful in contact with skin
H314Causes severe skin burns and eye damage
H317May cause an allergic skin reaction
H318Causes serious eye damage
H330Fatal if inhaled
H331Toxic if inhaled
H332Harmful if inhaled
H351Suspected of causing cancer
H371May cause damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H402Harmful to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P391Collect spillage.
P403Store in a well-ventilated place.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P364Take off immediately all contaminated clothing and wash it before reuse.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29310095
UN Number1736
ADR Class8
Packing GroupII
Storage Class6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany)1