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Norfloxacin

CAS Number
70458-96-7
EC Number
274-614-4
Chemical Formula
C16H18FN3O3
Molecular Weight
319.33 g/mol

Description

Norfloxacin (CAS 70458-96-7 ) is a second-generation fluoroquinolone antibiotic active ingredient used in pharmaceutical manufacturing. It functions as a broad-spectrum antibacterial agent targeting both gram-positive and gram-negative organisms. This makes it a core API in finished dosage form production for global markets. In pharmaceutical formulation, it is the active ingredient in oral tablets and suspensions indicated for urinary tract and gastrointestinal bacterial infections. Ophthalmic and otic preparations incorporate it as the primary antibacterial component in drops and solutions for ocular and ear infections. Contract manufacturers and generic drug producers source it as a pharmaceutical intermediate. It is frequently used for the synthesis of related fluoroquinolone derivatives in laboratory settings. Topical antimicrobial formulations in the personal care and pharmaceutical space also utilize it for preservation and infection control. These applications are specific to regulated product categories requiring high-purity ingredients. The product is supplied as a white to pale yellow crystalline powder for industrial use. It is available in pharmaceutical-grade specifications. These include USP , BP , and Ph. Eur. standards, with purity levels typically at 99% or above to meet API requirements. Bulk quantities are standard for industrial and contract manufacturing procurement. Smaller research-grade quantities are also available through specialty chemical distributors for testing. This ensures that manufacturers can maintain consistent quality across various production scales and regulatory environments. Contact us for supply of Norfloxacin Request Quote

Other Names (Synonyms)

Quinabic | Noroxin | NFLX | MK-366 | Chibroxin | Baccidal | 1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point227-228 °C
Boiling Point555.8±50.0 °C(Predicted)
Density1.2504 (estimate)
AppearanceOff-white to light yellow cryst powder
ColorWhite to yellow
FormCrystalline Powder
Water SolubilitySoluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water

Safety & Handling

Danger
GHS05· CorrosiveGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H318Causes serious eye damage
H319Causes serious eye irritation
H361Suspected of damaging fertility or the unborn child

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29335900
WGK (Germany)2