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Furosemide

CAS Number
54-31-9
EC Number
200-203-6
Chemical Formula
C12H11ClN2O5S
Molecular Weight
330.74 g/mol

Description

Furosemide (CAS 54-31-9 ), also known commercially as Lasix, is an active pharmaceutical ingredient (API) in the loop diuretic class. It is used in the manufacture of finished dosage forms targeting fluid retention and edema-related conditions. This material is utilized across human and veterinary pharmaceutical markets. Furosemide is the primary API in oral tablet formulations, where it is manufactured at standardized strengths for prescription drug products. Injectable solution manufacturing represents a distinct supply channel, requiring high-purity pharmaceutical-grade material compatible with parenteral processing standards. This ensures safety and efficacy in clinical settings. Veterinary pharmaceutical producers source this ingredient for companion animal and livestock formulations. It is particularly effective for cardiac and renal indications within the animal health sector. The compound also serves as a reference standard and analytical reagent in QC laboratories. These facilities use it for validating diuretic drug products and ensuring consistent manufacturing quality. The product is supplied as a white to off-white crystalline powder. Pharmaceutical-grade material is available to USP , BP , and Ph. Eur. specifications, which are the primary standards required. Bulk API is typically offered in kilogram and multi-kilogram quantities to meet industrial demand. Documentation packages include CoA, DMF references, and GMP certification to support regulatory submissions. Contact us for supply of Furosemide Request Quote

Other Names (Synonyms)

4-chloro-N-furfuryl-5-sulfamoylanthranilic acid | 4-chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid | 4-chloro-5-sulfamoyl-N-furfuryl-anthranilic acid | 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid | Frusemide | Lasix | Furosemid | Errolon

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point206 °C
Boiling Point582.1±60.0 °C(Predicted)
Density1.594 g/cm³ (solid)
Flash Point11 °C
Appearancewhite to light yellow crystal powde
ColorWhite to Off-White
Formpowder
Water SolubilitySoluble in acetone, DMF or methanol. Slightly soluble in water
Refractive Index1.6580 (estimate)

Safety & Handling

Danger
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2935904000
UN Number1230
ADR Class3
Packing GroupII
Storage Class6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany)3