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Posaconazole

CAS Number
171228-49-2
EC Number
682-747-8
Chemical Formula
C37H42F2N8O4
Molecular Weight
700.8 g/mol

Description

Posaconazole (CAS 171228-49-2 ), also referenced in development literature as SCH 56592, is a broad-spectrum triazole antifungal active pharmaceutical ingredient marketed under the brand name Noxafil. It targets invasive fungal infections caused by Aspergillus and Candida species, positioning it as a critical API in antifungal therapy manufacturing for global pharmaceutical supply chains. Posaconazole is formulated into oral suspensions, delayed-release tablets, and intravenous solutions for prophylaxis and treatment of invasive fungal infections in immunocompromised patients. Pharmaceutical manufacturers source it as an API for finished dosage form production under GMP conditions. In biotechnology, it is used as a reference standard for antifungal susceptibility testing. Contract development organizations also use this compound in formulation development work targeting improved bioavailability delivery systems and advanced drug interaction studies in clinical research. The product is supplied as a white to off-white crystalline powder. It is available in research-grade and GMP-compliant pharmaceutical-grade specifications to meet the requirements of regulated drug manufacturing. Our material meets rigorous quality standards including USP and EP requirements. Quantities range from small research lots through commercial-scale API batches for industrial use. Documentation packages including CoA, impurity profiles, and regulatory support files are available upon request to ensure full compliance with international pharmaceutical manufacturing protocols. Contact us for supply of Posaconazole Request Quote

Other Names (Synonyms)

Noxafil | Sch 56592 | Schering 56592

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point171.00 °C
Boiling Point850.7±75.0 °C(Predicted)
Density1.36±0.1 g/cm3(Predicted)
Flash Point9°C
AppearanceWhite Solid
Colorwhite to beige
Formpowder

Safety & Handling

Danger
GHS07· IrritantGHS08· Health HazardGHS09· Environment

Hazard Statements

H319Causes serious eye irritation
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P391Collect spillage.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code3204.90.0000
UN Number1230
Packing GroupII
WGK (Germany)3