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Olmesartan medoxomil

CAS Number
144689-63-4
EC Number
604-433-1
Chemical Formula
C29H30N6O6
Molecular Weight
558.6 g/mol

Description

Olmesartan medoxomil (CAS 144689-63-4 ), also marketed under the brand names Benicar and Olmetec, is an angiotensin II receptor blocker (ARB) prodrug used as an active pharmaceutical ingredient in antihypertensive formulations. Developed under the research code CS-866, it is a finished API supplied to generic and branded pharmaceutical manufacturers for oral solid dosage development. The primary application is in the manufacture of oral tablets. For the treatment of hypertension, it is formulated as a standalone or combination product, commonly paired with amlodipine or hydrochlorothiazide. Generic drug manufacturers source this API to develop bioequivalent products. This sourcing typically follows patent expiry in key regulated markets. Contract development and manufacturing organizations (CDMOs) use it in formulation development projects requiring ICH-compliant API characterization. Stability profiling is a critical component of these projects. Pharmaceutical importers and distributors also source it for supply into regulated markets requiring DMF or CEP documentation support for their filings. Olmesartan medoxomil is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications aligned with USP , BP , and Ph. Eur. monographs for global compliance. Standard commercial pack sizes range from small quantities for R&D use to bulk quantities for commercial manufacturing batches. This ensures flexibility for both pilot studies and full-scale pharmaceutical production lines. Contact us for supply of Olmesartan medoxomil Request Quote

Other Names (Synonyms)

Benicar | Olmetec | CS-866 | 6M97XTV3HD | 1,3-Dioxole, 1H-imidazole-5-carboxylic acid deriv.

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point184.14 °C
Boiling Point804.2±75.0 °C(Predicted)
Density1.38±0.1 g/cm3(Predicted)
Flash Point180°C
AppearanceWhite to off-white crystalline powder
Colorwhite to beige
Formpowder

Safety & Handling

Danger
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H312Harmful in contact with skin
H319Causes serious eye irritation
H332Harmful if inhaled
H360May damage fertility or the unborn child

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2934990002
Storage Class11 - Combustible Solids
WGK (Germany)3