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Sumatriptan succinate

CAS Number
103628-48-4
EC Number
600-463-4
Chemical Formula
C14H21N3O2S.C4H6O4
Molecular Weight
413.5 g/mol

Description

Sumatriptan succinate (CAS 103628-48-4 ) is the succinate salt form of sumatriptan, a selective serotonin receptor agonist used as the active pharmaceutical ingredient in acute migraine and cluster headache treatments. The salt form offers improved stability and solubility characteristics that are critical for pharmaceutical dosage form development. The primary application is as an API in prescription migraine therapies. It is formulated into tablets, nasal sprays, and subcutaneous injection products for rapid symptom relief. Pharmaceutical manufacturers source this compound for solid oral dosage forms where precise particle size is required. Polymorphic consistency directly affects bioavailability and dissolution performance in these formulations. Contract development organizations use it in reformulation projects targeting modified-release or needle-free delivery platforms. It is also procured by generic drug manufacturers developing bioequivalent products to reference-listed branded formulations. The material is available as a white to off-white crystalline powder for industrial use. It is supplied in pharmaceutical-grade specifications conforming to USP and BP monographs. Documentation packages typically include CoA, DMF references, and ICH-compliant impurity profiles. Packaging is offered in quantities ranging from research-scale grams to commercial kilogram lots. This ensures flexibility for both pilot-scale development and full-scale commercial manufacturing requirements. Contact us for supply of Sumatriptan succinate Request Quote

Other Names (Synonyms)

sumatriptan hydrogen succinate | 3-(2-(Dimethylamino)ethyl)-N-methylindole-5-methanesulfonamide succinate | Sumavel DosePro | Alsuma | Onzetra Xsail | Imitrex Statdose | GR 43175C | Zembrace SymTouch

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point165-166 °C
AppearanceWhite Crystalline Powder
Colorwhite to off-white
Formsolid

Safety & Handling

Danger
GHS05· CorrosiveGHS08· Health Hazard

Hazard Statements

H318Causes serious eye damage
H361Suspected of damaging fertility or the unborn child
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29350090
WGK (Germany)3