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Benzyl nicotinate

CAS Number
94-44-0
EC Number
202-332-3
Chemical Formula
C13H11NO2
Molecular Weight
213.23 g/mol

Description

Benzyl nicotinate (CAS 94-44-0 ) is an ester of nicotinic acid used primarily as a topical vasodilator active in pharmaceutical and cosmetic formulations. Known commercially as nicotinic acid benzyl ester, it produces a localized warming response. Formulators exploit this flushing effect in rubefacient and skin-conditioning products. In pharmaceutical topical preparations, it is incorporated into creams, gels, and patches designed to promote circulation in muscle and joint relief products. Cosmetic formulators use it in warming massage oils, body slimming creams, and anti-cellulite treatments where a controlled hyperemic effect is the intended consumer experience. It also appears as a fragrance modifier and fixative. In select perfumery applications, its ester character contributes to blending stability. At the intermediate level, it serves as a building block in the synthesis of more complex nicotinic acid derivatives for pharmaceutical R&D pipelines. The compound is supplied as a white to off-white crystalline powder or as a pale liquid depending on purity and processing conditions. It is available in pharmaceutical-grade and cosmetic-grade specifications for various uses. High-purity material typically exceeds 98% as confirmed by HPLC. Packaging options range from kilogram-scale laboratory quantities to bulk commercial orders for industrial formulators requiring consistent supply chains. Contact us for supply of Benzyl nicotinate Request Quote

Other Names (Synonyms)

phenylmethyl 3-pyridinecarboxylate | Nicotinic acid benzyl ester | benzyl pyridine-3-carboxylate | 3-pyridinecarboxylic acid phenylmethyl ester | Rubriment | Pycaril | Pykaryl | S497LCF9C9

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point24 °C
Boiling Point165 °C @ Press: 2 Torr
Density1,1165 g/cm 3
Flash Point170°C
ColorColourless to Light Beige
Formneat
Refractive Indexn 20/D 1.570
Log P2.400

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary Statements

P264Wash … thoroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code2933399990
Storage Class11 - Combustible Solids
WGK (Germany)2