HomeProducts

Hexyl nicotinate

CAS Number
23597-82-2
EC Number
245-767-4
Chemical Formula
C12H17NO2
Molecular Weight
207.27 g/mol

Description

Hexyl nicotinate (CAS 23597-82-2 ), also known as nicotinic acid hexyl ester, is an ester of nicotinic acid used as a penetration enhancer and carrier in topical formulations. It promotes localized vasodilation at the skin surface, making it a functional active in cosmetic and pharmaceutical products targeting circulation and warmth response for various applications. In topical pharmaceutical formulations, it is incorporated into creams and gels designed to produce a warming or flushing sensation, commonly used in muscle rub and sports recovery products. Cosmetic formulators use it in anti-cellulite creams and body contouring products where visible skin redness and improved microcirculation are desired endpoints for the end user. It also functions as a carrier and penetration enhancer, improving transdermal delivery of co-formulated actives through the skin barrier to ensure maximum efficacy of the final product. In pharmaceutical intermediate applications, it serves as a building block for synthesizing nicotinic acid derivatives and related heterocyclic compounds used in advanced chemical synthesis. The product is supplied as a clear to pale yellow liquid. It is available in technical and cosmetic-grade specifications, with purity levels typically at 98% or higher confirmed by GC analysis. Packaging options generally range from small laboratory quantities up to bulk drum supply for industrial formulators, ensuring flexible logistics for different manufacturing requirements. Contact us for supply of Hexyl nicotinate Request Quote

Other Names (Synonyms)

nicotinic acid hexyl ester | 3-pyridinecarboxylic acid hexyl ester | Hexyl 3-pyridinecarboxylate | BN07PB44IV | HYGROPLEX HHG | Nicotherm

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Boiling Point140 °C @ Press: 5.0 Torr
Density1.0133 g/cm³ @ Temp: 25 °C
ColorColorless to Almost colorless
Formclear liquid
Water Solubility0.17g/L(32 ºC)
Refractive Index1.4880 to 1.4920
Log P3.510

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29333990