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Methyl nicotinate

CAS Number
93-60-7
EC Number
202-261-8
Chemical Formula
C7H7NO2
Molecular Weight
137.14 g/mol

Description

Methyl nicotinate (CAS 93-60-7 ), also known commercially as Heat Spray in topical applications, is the methyl ester of nicotinic acid used across pharmaceutical synthesis, flavor formulation, and cosmetic actives. FEMA 3709 status confirms its recognized standing as a flavoring agent in food and beverage applications. In pharmaceutical manufacturing, it serves as a key intermediate in the synthesis of niacin derivatives. It is utilized in active pharmaceutical ingredients targeting metabolic pathways. Food and beverage formulators use it as a flavoring agent, contributing roasted, meaty, or savory nuance to processed food products. In personal care and cosmetic formulations, its vasodilatory effect on skin microcirculation makes it a functional active in warming creams, sports massage products, and topical heat-effect preparations. Fragrance and flavor houses also source it as a building block for heterocyclic aroma compounds in tobacco and savory flavor profiles. Methyl nicotinate is supplied as a white to off-white crystalline solid. Standard commercial grades include technical, food-grade, and pharmaceutical-grade material meeting USP or BP specifications. This ensures high purity for sensitive industrial and medical applications. Packaging typically ranges from kilogram quantities up to bulk drum supply depending on grade and application requirements. We ensure consistent quality and supply chain reliability for all global shipments. Contact us for supply of Methyl nicotinate Request Quote

Other Names (Synonyms)

Nicotinic acid, methyl ester | Methyl 3-pyridinecarboxylate | Heat spray | 3-pyridinecarboxylic acid methyl ester | 3-(Methoxycarbonyl)pyridine | 3-(Carbomethoxy)pyridine | methyl pyridine-3-carboxylate | Nicometh

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point42.5 °C
Boiling Point102-104 °C @ Press: 15 Torr
Density1.2528 (rough estimate)
Flash Point204 °F
Appearancewhite to brownish crystals or crystalline powder
ColorWhite to brownish
Odorat 10.00 % in dipropylene glycol. warm herbal tobacco
FormCrystals or Crystalline Powder
Water SolubilityNEGLIGIBLE
Vapor Pressure0.4 hPa (25 °C)
Refractive Index1.5323 (estimate)
Log P0.68 at 25℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary Statements

P264Wash … thoroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P321Specific treatment (see … on this label).
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29333999
WGK (Germany)3