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Nicotinamide

CAS Number
98-92-0
EC Number
202-713-4
Chemical Formula
C6H6N2O
Molecular Weight
122.12 g/mol

Description

Nicotinamide (CAS 98-92-0 ), also known as niacinamide and designated E375 in food applications, is the amide form of vitamin B3 used across pharmaceutical, nutritional, and cosmetic manufacturing. It functions as an active nutrient, skin-conditioning agent, and formulation stabilizer depending on the end market. In pharmaceutical manufacturing, it is used as an active ingredient in vitamin B3 supplements. It is found in multivitamin tablets and therapeutic preparations targeting pellagra and metabolic disorders. Food and beverage producers use it as an approved nutrient fortifier in cereals, infant formula, and functional drinks. In these applications, it restores or enhances B-vitamin content. Cosmetic formulators incorporate niacinamide into serums, moisturizers, and anti-aging creams for its ability to support skin barrier function. It helps reduce hyperpigmentation and also appears in feed premixes and veterinary nutritional products as a cost-effective B-vitamin source. The material is supplied as a white crystalline powder. It is available in both food-grade and pharmaceutical-grade specifications. Recognized quality standards include USP , BP , Ph. Eur. , and FCC , ensuring high purity for various industrial uses. Pharmaceutical grades are subject to stricter purity and heavy metal limits. Bulk supply is standard in 25 kg bags, with smaller packaging available for specialty or cosmetic-grade orders. Contact us for supply of Nicotinamide Request Quote

Other Names (Synonyms)

Vitamin B3 Niacinamide | pyridine-3-carboxamide | Niacinamide | NAM | E375

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point130 °C
Boiling Point157 °C @ Press: 5 x 10-4 Torr
Density1.400 g/cm³ @ Temp: 25 °C
Flash Point182 °C
AppearanceWhite crystalline powder
Colorwhite
OdorOdorless
Formpowder
Water Solubility1000 g/L (20 ºC)
Vapor Pressure0Pa at 25℃
Refractive Index1.4660 (estimate)
pH6.0-7.5 (50g/l, H2O, 20℃)
Log P-0.38 at 21℃

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29362990
UN Number1230
Packing GroupII
WGK (Germany)1