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Isobutylamine

CAS Number
78-81-9
EC Number
201-145-4
Chemical Formula
C4H11N
Molecular Weight
73.14 g/mol

Description

Isobutylamine (CAS 78-81-9 ), also known by its FEMA 4239 designation, is a primary aliphatic amine used as a reactive building block and process chemical across pharmaceutical synthesis and agrochemical manufacturing. It functions as an intermediate, pH regulator, and corrosion inhibitor depending on the process context. In agrochemical production, it serves as a key intermediate in synthesizing herbicides and pesticides. Its reactivity with acid chlorides and isocyanates enables the formation of active ingredient structures. Pharmaceutical manufacturers use it as a synthetic intermediate for drug compounds requiring a branched-chain amine moiety. In rubber and tire processing, it supports polymerization initiation and acts as an accelerator component in vulcanization systems. Water treatment formulators incorporate it for pH buffering and corrosion inhibition. These applications are critical in industrial cooling and boiler systems. The product is supplied as a clear, low-viscosity liquid in drum and IBC quantities, with bulk tanker options available for high-volume procurement. Technical grade is the standard commercial offering, with purity levels typically at 99% or higher. Pharmaceutical-grade material meeting relevant compendial specifications is available from select manufacturers. This material is suitable for regulated synthesis applications and meets high quality standards. Our logistics network ensures reliable delivery of this essential chemical intermediate to global manufacturing facilities. Contact us for supply of Isobutylamine Request Quote

Other Names (Synonyms)

Valamine | iso-C4H9NH2 | I-Butylamine | 3-Methyl-2-propylamine | 2-Methylpropylamine | 2-Methyl-1-Aminopropane | 1-Amino-2-methylpropane | IBA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point-85 °C
Boiling Point68-69 °C
Density0.724 g/cm³ @ Temp: 25 °C
Flash Point15 °F
AppearanceButyl amines are highly flammable, colorless liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. n-isomer:
ColorClear colorless to slightly yellow
OdorStrong ammoniacal.
FormLiquid
Water Solubilitysoluble
Vapor Pressure15.9kPa at 20℃
Refractive Indexn 20/D 1.397(lit.)
pH12.2 (100g/l, H2O, 20℃)
Log P-0.3 at 25℃

Safety & Handling

Danger
GHS02· FlammableGHS05· CorrosiveGHS06· ToxicGHS07· Irritant

Hazard Statements

H225Highly Flammable liquid and vapor
H301Toxic if swallowed
H302Harmful if swallowed
H311Toxic in contact with skin
H314Causes severe skin burns and eye damage
H318Causes serious eye damage
H331Toxic if inhaled
H335May cause respiratory irritation H301+H311+
H331Toxic if swallowed, in contact with skin or if inhaled

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P364Take off immediately all contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29211990
UN Number1214
ADR Class3
Packing GroupII
Storage Class3 - Flammable liquids
WGK (Germany)1