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Trimethylamine

CAS Number
75-50-3
EC Number
200-875-0
Chemical Formula
C3H9N
Molecular Weight
59.11 g/mol

Description

Trimethylamine (CAS 75-50-3 ), commonly abbreviated as TMA, is a tertiary amine supplied primarily in anhydrous form for industrial and specialty chemical applications. It functions as a key intermediate and reactant across pharmaceutical synthesis and food-grade flavoring. Its strong fishy odor profile is both a target compound and a process marker in various manufacturing sectors. FEMA 3241 status confirms its recognized standing as a flavoring substance in regulated food applications. In food and flavor manufacturing, TMA is used as a reference and active flavoring agent in seafood-type flavor systems. In these environments, its characteristic odor must be precisely controlled or replicated for consistency. Pharmaceutical producers use it as a building block in the synthesis of choline salts and quaternary ammonium compounds. Both of these appear frequently in finished drug formulations and nutritional supplements. It also functions as a catalyst and intermediate in the production of ion exchange resins and specialty chemicals. In preservation-related applications, TMA derivatives contribute to biocidal formulations targeting microbial control. Trimethylamine is supplied as a compressed anhydrous gas or as aqueous solution, typically at concentrations of 30 to 45 percent in water. Food-grade and technical-grade designations are the most commonly available specifications. Packaging ranges from pressurized cylinders for anhydrous supply to drum quantities for aqueous grades. This ensures safe handling and transport according to the specific requirements of the industrial or laboratory facility. Contact us for supply of Trimethylamine Request Quote

Other Names (Synonyms)

trimethylamine anhydrous | NMe3 | N(CH3)3 | N,N,N-trimethylamine | N,N-dimethyl-methanamine | N-trimethylamine | TMA | Methanamine, N,N-dimethyl-

Key Technical Features

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Physical Properties

Melting Point-117.1 °C
Boiling Point2.8 °C
Density0.627 g/cm³ @ Temp: 25 °C
Flash Point38 °F
AppearanceTrimethylamine is compressed gas or liquid. Flammable gas. Shipped as a compressed gas, it may be present in an aqueous solution. It has a strong, fishy, ammoniacal odor. The Odor Threshold is 0.00011-0.87 ppm. Warning: The Odor Threshold range is so broad that odor alone should not be used as a warning of potentially hazardous exposures.
ColorColorless
Odorsmelling like rotting fish, rotting eggs, garbage, or urine.
FormLiquid
Water SolubilitySoluble In Water, 8.9e+005 mg/L.
Vapor Pressure430 mm Hg ( 25 °C)
Refractive Indexn 20/D 1.357
pHa strong base (pH 9.8)
Log P0.06

Safety & Handling

Danger
GHS02· FlammableGHS04· Compressed GasGHS05· CorrosiveGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H220Extremely flammable gas
H224Extremely flammable liquid and vapor
H280Contains gas under pressure; may explode if heated
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H315Causes skin irritation
H318Causes serious eye damage
H320Causes eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H371May cause damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H402Harmful to aquatic life

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P222Do not allow contact with air.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P363Wash contaminated clothing before reuse.
P377Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P381In case of leakage, eliminate all ignition sources.
P403Store in a well-ventilated place.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P403Protect from sunlight. Store in a well-ventilated place.
P331Rinse mouth. Do NOT induce vomiting.
P354IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29211100
UN Number2924
ADR Class3
Packing GroupII
Storage Class2A - Gases
WGK (Germany)1