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Lidocaine hydrochloride

CAS Number
73-78-9
EC Number
200-803-8
Chemical Formula
C14H22N2O.ClH
Molecular Weight
270.80 g/mol

Description

Lidocaine hydrochloride (CAS 73-78-9 ) is the water-soluble salt form of lidocaine, the benchmark local anesthetic active used across injectable, topical, and dental pharmaceutical formulations. It is a regulated active pharmaceutical ingredient (API) sourced by formulators, contract manufacturers, and pharmaceutical importers operating under strict pharmacopoeial standards. In injectable pharmaceuticals, it is formulated into nerve block and epidural anesthetic solutions, requiring high-purity API meeting injectable-grade specifications for safety and efficacy. Topical formulations, including creams, gels, patches, and sprays, use it as the primary anesthetic active for pain and itch relief in OTC and prescription products across global markets. Dental cartridge manufacturers incorporate it into lidocaine-epinephrine combination solutions for procedural anesthesia. In cosmetic products, it appears in formulations targeting minor skin discomfort. Regulatory classification for these applications varies by market and concentration. Lidocaine hydrochloride is supplied as a white crystalline powder for easy integration into various bases. It is available in USP , BP , and Ph. Eur. grades to meet injectable and oral pharmaceutical requirements, with technical grade available for non-pharmaceutical applications. Packaging ranges from kilogram quantities for development and compounding use to bulk drums for commercial manufacturing, ensuring scalability for diverse industrial and medical needs. Contact us for supply of Lidocaine hydrochloride Request Quote

Other Names (Synonyms)

omega-Diethylamino-2,6-dimethylacetanilide hydrochloride | alpha-Diethylamino-2,6-acetoxylidine hydrochloride | 2-Diethylamino-2',6'-acetoxylidide hydrochloride | lidocaine hydrochloride anhydrous | LIDOCAINE HCL | Lignocaine hydrochloride | Xylocaine Viscous | Laryng-O-jet

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point77-78 °C
AppearanceWhite to Off-White Solid
ColorWhite to off-white
FormSolid
Water SolubilityWater : ≥ 36 mg/mL (132.94 mM)
Log P2.359 (est)

Safety & Handling

Danger
GHS06· ToxicGHS07· IrritantGHS08· Health Hazard

Hazard Statements

H301Toxic if swallowed
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H412Harmful to aquatic life with long lasting effects

Precautionary Statements

P233Keep container tightly closed.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284In case of inadequate ventilation wear respiratory protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P403Store in a well-ventilated place.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P316Get emergency medical help immediately.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.