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Amines REACH

Lidocaine

CAS Number
137-58-6
EC Number
200-179-1
Chemical Formula
C14H22N2O
Molecular Weight
234.34 g/mol

Description

Lidocaine (CAS 137-58-6 ), also known by the trade name Xylocaine®, is a synthetic amino amide compound used as a local anesthetic and topical analgesic across pharmaceutical and personal care applications. It functions by blocking nerve signal transmission, making it the active ingredient of choice in a broad range of prescription and OTC formulations. In pharmaceutical manufacturing, it is formulated into injectable solutions. These solutions are used for regional and local anesthesia in surgical, dental, and emergency care settings. Topical dosage forms including creams, gels, patches, and sprays rely on it as the active ingredient. These products deliver surface-level pain and itch relief in both prescription and consumer OTC products. Personal care and cosmetic formulators incorporate it into numbing creams used ahead of aesthetic procedures. Common uses include tattooing, laser treatments, and minor dermal interventions. It also appears as an active in combination formulations targeting premature ejaculation, hemorrhoid relief, and wound care. The material is supplied as a white crystalline powder in both free base and hydrochloride salt forms. The hydrochloride is the preferred grade for aqueous injectable and topical formulations due to its water solubility. Standard grades include USP , BP , and Ph.Eur. , with API-grade material supported by full regulatory documentation. This ensures compliance for pharmaceutical procurement and large-scale manufacturing. Contact us for supply of Lidocaine Request Quote

Other Names (Synonyms)

α-diethylamino-2,6-dimethylacetanilide | Xylocaine® | alpha-diethylamino-2,6-dimethylacetanilide | 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide | 2-(Diethylamino)-2',6'-acetoxylidide | Duncaine | Lidoderm | Esracaine

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point68.5 °C
Boiling Point159-160 °C @ Press: 2 Torr
Density1.026 g/cm³
Flash Point9°C
Appearancesolid
ColorWhite to slightly yellow
Formpowder
Water Solubilitypractically insoluble
Refractive Index1.5110 (estimate)
Log P2.440

Safety & Handling

Warning
GHS07· IrritantGHS08· Health Hazard

Hazard Statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H362May cause harm to breast-fed children
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy and while nursing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.

Trade & Regulatory

HS Code29242990
Storage Class11 - Combustible Solids
WGK (Germany)3