HomeProducts

Theophylline

CAS Number
58-55-9
EC Number
200-385-7
Chemical Formula
C7H8N4O2
Molecular Weight
180.16 g/mol

Description

Theophylline (CAS 58-55-9 ) is a methylxanthine compound used as an active pharmaceutical ingredient in respiratory therapeutics and as a reference standard in analytical and formulation development. Procurement is driven primarily by finished dosage form manufacturers and API suppliers operating under tightly controlled regulatory frameworks. In pharmaceutical manufacturing, it is formulated into bronchodilator tablets. It is also used in capsules and extended-release oral dosage forms targeting obstructive airway conditions. It serves as a buffering and pH-modulating agent in select injectable and liquid formulations. Cosmetic formulators incorporate it into topical products targeting cellulite and skin-firming claims. It functions as an active ingredient in caffeine-adjacent compound systems for specialized skincare. Analytical laboratories source it as a certified reference standard for HPLC method development and pharmacokinetic studies. Theophylline is supplied as a white crystalline powder in various forms. Standard grades include USP , BP , and Ph. Eur. , with anhydrous and hydrate specifications distinguished across pharmacopeias. Bulk quantities are available for API-scale manufacturing. Smaller quantities are offered for R&D and quality control applications. This ensures that both large-scale production and laboratory-scale testing requirements are met with high-purity material. Contact us for supply of Theophylline Request Quote

Other Names (Synonyms)

1,3-dimethylxanthine | 1,3-dimethyl-7H-purine-2,6-dione | 1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione | theophylline anhydrous | Theolair | Nuelin | 1H-Purine-2,6-dione, 3,9-dihydro-1,3-dimethyl- | 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point270 °C
Boiling Point312.97°C (rough estimate)
Density1.51 g/cm³ (crystal)
Flash Point11 °C
Appearancewhite to light yellow crystal powder
Colorwhite
Formpowder
Water Solubility8.3 g/L (20 ºC)
Refractive Index1.6700 (estimate)
Log P-0.020

Safety & Handling

Danger
GHS08· Health HazardGHS06· ToxicGHS07· Irritant

Hazard Statements

H301Toxic if swallowed
H302Harmful if swallowed
H360May damage fertility or the unborn child
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
H370Causes damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H402Harmful to aquatic life

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy and while nursing.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P316Get emergency medical help immediately.

Trade & Regulatory

HS Code29399900
UN Number2811
ADR Class6.1
Packing GroupIII
Storage Class6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany)1