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5-Hydroxytryptophan

CAS Number
56-69-9
EC Number
200-284-8
Chemical Formula
C11H12N2O3
Molecular Weight
220.22 g/mol

Description

5-Hydroxytryptophan (CAS 56-69-9 ), commercially known as 5-HTP, is a naturally occurring amino acid intermediate derived primarily from the seeds of Griffonia simplicifolia. In dietary supplement and nutraceutical manufacturing, it functions as a direct precursor to serotonin. This makes it a target active ingredient for mood, sleep, and appetite-related formulations. Supplement manufacturers use 5-HTP as the primary active in capsule, tablet, and softgel formats targeting sleep support and stress management. It is also utilized in weight management categories. In functional food and beverage development, it is incorporated into products where serotonin-pathway support is the intended positioning for the final consumer product. Cosmetic and personal care formulators apply it in anti-aging and skin-tone products. Its antioxidant activity supports formulation stability and skin conditioning claims across various topical applications and beauty-from-within solutions. Pharmaceutical-grade material is used in clinical research and as a reference standard in analytical method development. 5-HTP is supplied as a fine white to off-white powder with high solubility characteristics for diverse manufacturing needs. It is available in food-grade and pharmaceutical-grade specifications, with purity levels typically at 98% or higher confirmed by HPLC. Packaging ranges from small research quantities to bulk commercial volumes for global distribution. Material is commonly sourced to USP or BP -aligned quality standards to ensure safety and efficacy. Our supply chain ensures consistent potency and rigorous testing for heavy metals and microbiological contaminants in every batch. Contact us for supply of 5-Hydroxytryptophan Request Quote

Other Names (Synonyms)

5-HTP | DL-5-HTP | Tryptophan, 5-hydroxy- | 9181P3OI6N | 5-Hydroxytryptophane | Griffonia simplicifolia

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point298 °C (decomp)
Boiling Point361.16°C (rough estimate)
Density1.484
ColorOff-White to Pale Beige
Formsolid
Water SolubilitySoluble in water (4 mg/ml at 25°C), methanol.
Refractive Index1.5200 (estimate)
Log P-0.292 (est)

Safety & Handling

Danger
GHS02· FlammableGHS06· ToxicGHS07· Irritant

Hazard Statements

H226Flammable liquid and vapor
H301Toxic if swallowed
H302Harmful if swallowed
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P378Use … for extinction.
P235Store in a well-ventilated place. Keep cool.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

WGK (Germany)3