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L-hydroxyproline

CAS Number
51-35-4
EC Number
200-091-9
Chemical Formula
C5H9NO3
Molecular Weight
131.13 g/mol

Description

L-Hydroxyproline (CAS 51-35-4 ), commonly abbreviated as Hyp, is a non-essential amino acid derived primarily from collagen hydrolysis. It functions as a biochemical marker for collagen content and serves as a building block in peptide synthesis. In pharmaceutical manufacturing, Hyp is used as a reference standard and synthetic intermediate in the production of collagen-related peptides and drug compounds targeting connective tissue. It is essential for nutraceutical formulations and cosmetic actives development. Food and nutrition manufacturers incorporate it into collagen-based supplements, functional protein blends, and hydrolyzed collagen products where amino acid profile verification is required. This ensures high-quality standards for consumer health products. Personal care formulators use it as a moisturizing and stabilizing agent in anti-aging creams, serums, and skin-conditioning treatments where collagen support claims are commercially relevant. It helps maintain the structural integrity of topical applications. It also serves as an analytical reagent in quality control laboratories for quantifying collagen content in raw materials and finished products. This application is vital for maintaining consistency across various industrial manufacturing processes. L-Hydroxyproline is supplied as a white crystalline powder. It is available in USP , FCC , and reagent-grade specifications to meet the sourcing requirements of pharmaceutical, food, and cosmetic manufacturers. Bulk quantities are standard for industrial buyers, with smaller quantities available for R&D and QC applications. Our supply chain ensures that all technical requirements and quality benchmarks are met for every shipment. Contact us for supply of L-hydroxyproline Request Quote

Other Names (Synonyms)

trans-L-Hydroxyproline | trans-Hydroxyproline | trans-4-Hydroxyproline | LS-hydroxyproline | L-4-Hydroxyproline | Hypro | Hyp | Hydroxy-proline

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point274 °C
Boiling Point242.42°C (rough estimate)
Density1.478 g/cm³
AppearanceWhite crystalline powder
ColorWhite
OdorOdorless
FormCrystals or Crystalline Powder
Water Solubility357.8 g/L (20 º C)
Refractive Index-75.5 ° (C=4, H2O)
pH5.5-6.5 (50g/l, H2O, 20℃)
Log P-0.350 (est)

Safety & Handling

Warning
GHS07· Irritant

Hazard Statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29339990
Storage Class11 - Combustible Solids
WGK (Germany)3