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Hydroxylamine hydrochloride

CAS Number
5470-11-1
EC Number
226-798-2
Chemical Formula
ClH.H3NO
Molecular Weight
69.49 g/mol

Description

Hydroxylamine hydrochloride (CAS 5470-11-1 ), also known as hydroxylammonium chloride, is a stable, water-soluble salt form of hydroxylamine used across pharmaceutical synthesis, polymer chemistry, and analytical applications. It functions primarily as a reducing agent, oxime-forming reagent, and chemical intermediate in multi-step synthesis processes. In pharmaceutical manufacturing, it converts ketones and aldehydes into oximes. This conversion is a critical step in producing active pharmaceutical ingredients and synthesis intermediates. Polymer producers use it as an antioxidant stabilizer and polymerization inhibitor to control degradation. It is particularly effective in nylon and other engineering plastics. In biotechnology and life sciences, it serves as a selective protein-cleaving reagent for Asn-Gly bond cleavage in peptide mapping workflows. Analytical chemists rely on it for metal ion detection and as a reducing agent in sample preparation protocols. Hydroxylamine hydrochloride is supplied as a white crystalline powder for various uses. It is available in pharmaceutical-grade ( USP / BP ) specifications for regulated synthesis applications, as well as technical grade for industrial and polymer processing use. Packaging ranges from small laboratory quantities to bulk industrial volumes, with purity levels typically at 98% or higher depending on the specific grade required for the application. Contact us for supply of Hydroxylamine hydrochloride Request Quote

Other Names (Synonyms)

Hydroxylammonium chloride | Oxammonium hydrochloride | Hydroxyamine hydrochloride | Hydroxylamine chloride (1:1) | 5X4ZA62Z4Q | HYDROXYLAMINE CHLOROHYDRATE | RefChem:5895

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point151 °C (decomp)
Density1.7 g/cm³
AppearanceWhite crystals
ColorWhite to off-white
FormLiquid
Water Solubility560 g/L (20 ºC)
Vapor Pressure0.054 Pa (50 °C)
pH2.5-3.5 (25℃, 50mg/mL in H2O)
Log P-0.810 (est)

Safety & Handling

Warning
GHS05· CorrosiveGHS07· IrritantGHS08· Health HazardGHS09· EnvironmentGHS06· Toxic

Hazard Statements

H290May be corrosive to metals
H301Toxic if swallowed
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
H371May cause damage to organs
H372Causes damage to organs through prolonged or repeated exposure
H373May causes damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
H410Very toxic to aquatic life with long lasting effects
H412Harmful to aquatic life with long lasting effects H302+
H312Harmful if swallowed or in contact with skin

Precautionary Statements

P203Obtain, consult and follow expert instructions for use.
P234Keep only in original packaging.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P318IF exposed or concerned, get medical advice.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P390Absorb spillage to prevent material damage.
P391Collect spillage.
P405Store locked up.
P406Store in a corrosion-resistant/… container with a resistant inner liner.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316Get emergency medical help immediately.
P317Get emergency medical help.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code28251000
UN Number2923
ADR Class8
Packing GroupII
Storage Class4.1A - Other explosive hazardous materials
WGK (Germany)3