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Hydroxyphenoxy propionic acid

CAS Number
94050-90-5
EC Number
407-960-3
Chemical Formula
C9H10O4
Molecular Weight
182.17 g/mol

Description

Hydroxyphenoxy propionic acid (CAS 94050-90-5 ), commercially identified by the abbreviation D-HPPA, is a chiral phenoxypropionic acid derivative used as a building block in pharmaceutical synthesis and specialty formulation. Its defined stereochemistry makes it a controlled starting material where enantiomeric purity directly affects downstream product performance. In pharmaceutical manufacturing, D-HPPA serves as a key intermediate in synthesis. It is particularly useful in the synthesis of optically active active pharmaceutical ingredients where a resolved chiral center is required from the outset. Personal care formulators incorporate it into stabilizer systems. The phenolic functionality contributes to oxidative protection in finished products. Its UV-stabilizing properties are relevant in topical formulations and cosmetic preparations requiring extended shelf stability under light exposure. The compound also appears in research and development pipelines targeting biocidal or preservative actives derived from hydroxyphenoxy scaffolds. D-HPPA is typically supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade specifications with documented enantiomeric excess, which is the critical quality parameter for procurement in regulated synthesis workflows. Packaging ranges from laboratory-scale to kilogram lots. Contact us for supply of Hydroxyphenoxy propionic acid Request Quote

Other Names (Synonyms)

(R)-2-(4-Hydroxyphenoxy)propanoic acid | (R)-(+)-2-(4-Hydroxyphenoxy)propionic acid | (2R)-2-(4-hydroxyphenoxy)propanoic acid | Radianskin PW LS | Propanoic acid, 2-(4-hydroxyphenoxy)-, (2R)- | (R)-2-(p-hydroxyphenoxy)propionic acid | WSI8A5QG10 | Propanoic acid, 2-(4-hydroxyphenoxy)-, (R)- | D-HPPA

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point145-148 °C (lit.)
Boiling Point367.5±17.0 °C(Predicted)
Density1.302±0.06 g/cm3(Predicted)
ColorOff-White
FormSolid
Refractive Index38 ° (C=0.1, MeOH)

Safety & Handling

Danger
GHS05· Corrosive

Hazard Statements

H318Causes serious eye damage

Precautionary Statements

P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P265Wash … thoroughly after handling.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29189900
Storage Class11 - Combustible Solids
WGK (Germany)1