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L-5-Hydroxytryptophan

CAS Number
4350-09-8
EC Number
224-411-1
Chemical Formula
C11H12N2O3
Molecular Weight
220.22 g/mol

Description

L-5-Hydroxytryptophan (CAS 4350-09-8 ), commonly known as 5-HTP and commercially sourced as Oxitriptan or Griffonia Seed Extract, is a naturally occurring amino acid precursor used across pharmaceutical, nutraceutical, and functional food manufacturing. It is commercially extracted from the seeds of Griffonia simplicifolia and serves as a direct biosynthetic precursor to serotonin, making it a primary active ingredient in mood and sleep support formulations. In nutraceutical manufacturing, 5-HTP is the core active in dietary supplement capsules and tablets targeting sleep quality, appetite regulation, and mood balance. Functional food and beverage formulators incorporate it into fortified products. Pharmaceutical-grade material is used in clinical and OTC product development, particularly in markets where Oxitriptan is recognized as an established API. It meets rigorous quality standards for global distribution. Cosmetic formulators have adopted it in premium skincare lines for its antioxidant activity, positioning it in anti-aging serums and moisturizing treatments. This versatility makes it a valuable raw material for diverse industries. 5-HTP is supplied as a fine white to off-white powder. Standard commercial grades include food-grade and pharmaceutical-grade specifications, with purity levels typically at 98% or higher by HPLC analysis. Material derived from Griffonia seed extract is the dominant commercial form and is available with supporting documentation for botanical traceability. Our supply chain ensures consistent quality and reliable lead times for bulk orders. Contact us for supply of L-5-Hydroxytryptophan Request Quote

Other Names (Synonyms)

Oxitriptan | Griffonia Seed Extract | Griffonia Seed Extract (5-htp) | (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid | 5-Hydroxy-L-tryptophan | 5-HTP

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point273 °C (decomp)
Boiling Point361.16°C (rough estimate)
Density0.902 g/mL at 25 °C(lit.)
Flash Point175 °F
Appearancewhite to pale grey powder
Colorwhite
Formsolid
Water SolubilitySlightly soluble
Refractive Indexn 20/D 1.4850(lit.)
Log P-0.140 (est)

Safety & Handling

Danger
GHS06· ToxicGHS07· Irritant

Hazard Statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary Statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash … thoroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P319Get medical advice/attention if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P316Get emergency medical help immediately.
P352IF ON SKIN: Wash with plenty of water.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317Get emergency medical help.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P364Take off contaminated clothing and wash it before reuse.
P233Store in a well-ventilated place. Keep container tightly closed.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29339990
UN Number2811
ADR Class6.1
Packing GroupIII
Storage Class6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany)3