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tert-butyl acetate

CAS Number
540-88-5
EC Number
208-760-7
Chemical Formula
C6H12O2
Molecular Weight
116.16 g/mol

Description

Tert-butyl acetate ( CAS 540-88-5 ), commonly abbreviated as TBAc, is a slow-evaporating ester solvent used across pharmaceutical synthesis, coatings, and specialty chemical manufacturing. Its low HAP classification under U.S. EPA regulations makes it a preferred alternative to conventional ketone and aromatic solvents in regulated production environments. In pharmaceutical manufacturing, TBAc functions as a reaction solvent and intermediate in peptide synthesis and API processing, where controlled evaporation rates support yield and purity targets. Coatings and ink formulators use it as a carrier solvent to improve flow, leveling, and film formation in high-solids systems. In fragrance compounding, TBAc contributes a clean, fruity character. This material is suitable for fine fragrance and personal care applications. It also appears in flavor formulations where a mild, apple-like ester note is required at low use levels. TBAc is supplied as a clear liquid in drum and IBC quantities, with bulk tanker options available for high-volume industrial buyers. Standard commercial grades meet technical specifications. Pharmaceutical-grade material is available to meet USP and BP requirements for API and drug product applications. Buyers should confirm solvent residual class compliance. When sourcing for regulated pharmaceutical use, ensure the material meets EP or Ph.Eur. standards. This ensures the highest level of safety and performance in your manufacturing process. Contact us for supply of tert-butyl acetate Request Quote

Other Names (Synonyms)

tert-butyl ester of acetic acid | t-butyl acetate | Acetic acid, 1,1-dimethylethyl ester | Texaco lead appreciator | Acetic acid, tert-butyl ester | 1,1-Dimethyl acetate | 76N22HKP3X | TBAc

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

Physical Properties

Melting Point<25 °C
Boiling Point97.8 °C
Density0.8593 g/cm³ @ Temp: 25 °C
Flash Point60 °F
AppearanceButyl acetates are colorless or yellowish liquids with pleasant, fruity odors. There are 4 isomers.
ColorClear colorless
OdorFruity
FormLiquid
Water Solubilityinsoluble
Vapor Pressure41 hPa (20 °C)
Refractive Indexn 20/D 1.386(lit.)
Log P1.64 at 21.7℃

Safety & Handling

Danger
GHS02· FlammableGHS07· Irritant

Hazard Statements

H225Highly Flammable liquid and vapor
H320Causes eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H336May cause drowsiness or dizziness

Precautionary Statements

P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233Keep container tightly closed.
P240Ground and bond container and receiving equipment.
P241Use explosion-proof equipment.
P242Use non-sparking tools.
P243Take action to prevent static discharges.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P317Get emergency medical help.
P319Get medical advice/attention if you feel unwell.
P405Store locked up.
P501Dispose of contents/container in accordance with local regulations.
P265Wash … thoroughly after handling.
P340IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P378Use … for extinction.
P233Store in a well-ventilated place. Keep container tightly closed.
P235Store in a well-ventilated place. Keep cool.
P353IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code29153990
UN Number1123
ADR Class3
Packing GroupII
Storage Class3 - Flammable liquids
WGK (Germany)1